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A low or slow-rising hCG level can be a sign of an ectopic pregnancy, but looking at hCG levels alone is not usually enough for a doctor to make the diagnosis. While a slow-rising or low hCG level can indicate an ectopic pregnancy, it does not mean that you are definitely experiencing one. There are other reasons for slow-rising hCG levels. If the pregnancy cannot be visualized at all, the pregnancy might be ectopic, depending on the hCG levels. If the hCG levels are above 1,800 and the embryo cannot be visualized in the womb, the suspicion for an ectopic pregnancy increases dramatically.
Normal vs. Slow Rising hCG. Beta human chorionic gonadotropin (β-hCG) can be detected in pregnancy as early as eight days after ovulation.14The rate of increase in β-hCG levels, typically measured every 48 hours, can aid in. In early pregnancy, an increase in serum hCG of less than a minimal threshold in 48 hours is suspicious of an abnormal pregnancy (ectopic or early pregnancy loss) because 99% of normal intrauterine pregnancies will have a rate of increase faster than this minimum. Laboratory decoding of hCG in ectopic pregnancy according to the results of a blood test is considered the most accurate and reliable.
It shows an increase in the level of this hormone 4 days after fertilization and even earlier. The level of hCG in the blood during normal pregnancy is more than 15 mIU / ml. The great diagnostic value of serum beta-HCG is emphasized in the cases of old disturbed ectopic pregnancies accompanied by mild and uncommon symptoms and very low beta-HCG levels.
In case of unruptured pregnancies or tubal rupture the diagnosis is verified before the result is available by the clinical and sonographic data. The first and most useful basic test for diagnosing an ectopic pregnancy is a urinary pregnancy test. Because these tests are reliant on the hormone Human Chorionic Gonadotropin (hCG), a hormone produced by a fertilised egg after conception, these can sometimes produce a false negative result because the hormone is not present in high enough levels to test positively. 439 rows · Jan 11, 2020 · According to this review, serum CPK level can be used as a diagnostic. Diagnosis of ectopic pregnancy.
Although much is made of blood hCG levels and ultrasound studies, the clinical impression of the gynecologist or reproductive endocrinologist is the most important factor in making a timely diagnosis of ectopic pregnancy. There is no significant difference in the morphology of ectopic pregnancy between the two patterns of β hCG clearance. In group 1 the average half life of β hCG clearance was 82.5 hours (±SD 50.2).
In group 2 the average half life of β hCG clearance, in the decline phase of the curve, was 106.7 hours (±SD 72.0).
List of related literature:
|from Textbook of Family Medicine E-Book|
|from Crush Step 1 E-Book: The Ultimate USMLE Step 1 Review|
|from The Reproductive System at a Glance|
|from The New Harvard Guide to Women’s Health|
|from Sonography Exam Review: Physics, Abdomen, Obstetrics and Gynecology E-Book|
|from Conn’s Current Therapy 2010 E-Book: Expert Consult|
|from Comprehensive Gynecology E-Book|
|from Perinatal Nursing|
|from Hacker & Moore’s Essentials of Obstetrics and Gynecology E-Book|
|from Manual of Obstetrics E-book|