Zika Might Be Associated with Autoimmune Brain Disorder, Study States

 

Schizophrenia May Be an Autoimmune Condition

Video taken from the channel: SciShow Psych


 

Zika virus linked to more neurological conditions

Video taken from the channel: Al Jazeera English


 

Autoimmune Encephalitis Resembling Dementia Syndromes

Video taken from the channel: The Encephalitis Society


 

Brazilian scientists find new Zika-linked brain disorder in adults

Video taken from the channel: ARIRANG NEWS


 

Does Psychological Stress Trigger Autoimmune Disorders? Medpage Today

Video taken from the channel: MedPage Today


 

When The Immune System Attacks The Brain Antineuronal Antibodies Discovered in a Case of Mania

Video taken from the channel: PsychScene Hub


 

Autoimmune neurological disease research: Mayo Clinic Radio

Video taken from the channel: Mayo Clinic


Now, a new study reports a possible link between Zika and an autoimmune disorder known as acute disseminated encephalomyelitis (ADEM). Now, a new study reports a possible link between Zika and an autoimmune disorder known as acute disseminated encephalomyelitis (ADEM). In this disease, the immune system attacks the coating (myelin) around nerve fibers in the brain and spinal cord, much like multiple sclerosis. Now, a new study reports a possible link between Zika and an autoimmune disorder known as acute disseminated encephalomyelitis (ADEM). In this disease, the immune system attacks the coating (myelin) around nerve fibers in the brain and spinal cord, much like multiple sclerosis.

Now, a new study reports a possible link between Zika and an autoimmune disorder known as acute disseminated encephalomyelitis (ADEM). Zika has already been linked with the autoimmune disorder Guillain-Barre that causes swelling in the brain and spinal cord that damages the myelin, a white protective coating that surrounds never. The mosquito-borne virus is already suspected of causing a birth defect called microcephaly characterized by an abnormally small head and brain and a nervous system disorder called Guillain-Barre syndrome. Now, a new study reports a possible link between Zika and an autoimmune disorder known as acute disseminated encephalomyelitis (ADEM).

Existing research and case studies suggest the Zika virus is linked to GBS. There is also a strong body of research suggesting the virus can also cause microcephaly, a condition in which a baby has. Now, according to a small study being released Monday at the American Academy of Neurology’s 68th annual meeting in Vancouver, Canada, scientists say Zika may also cause an autoimmune syndrome called acute disseminated encephalomyelitis (ADEM).

The Zika virus, they say, closely resembles some infectious agents that have been linked to the development of autism, bipolar disorder and schizophrenia. Schizophrenia and other debilitating. Previous research has suggested that the mosquito-transmitted Zika virus also appears to be linked to microcephaly, a birth defect that causes babies to be born with unusually small heads and.

List of related literature:

There is also concern that Zika virus infection may be associated with the development of Guillain-Barré syndrome (Chapter 39: Viral Syndromes).

“Fenner and White's Medical Virology” by Christopher J. Burrell, Colin R. Howard, Frederick A. Murphy
from Fenner and White’s Medical Virology
by Christopher J. Burrell, Colin R. Howard, Frederick A. Murphy
Elsevier Science, 2016

CDC concludes Zika causes microcephaly and other brain defects.

“Epidemiology 101” by Friis
from Epidemiology 101
by Friis
Jones & Bartlett Learning, 2017

However, the best studied example is that of measles virus in the brain associated with measles inclusion body encephalitis or subacute sclerosing panencephalitis.

“The Dictionary of Virology” by Brian W.J. Mahy
from The Dictionary of Virology
by Brian W.J. Mahy
Elsevier Science, 2009

Guillain-Barré syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study.

“Hunter's Tropical Medicine and Emerging Infectious Diseases E-Book” by Edward T Ryan, David R Hill, Tom Solomon, Timothy P Endy, Naomi Aronson
from Hunter’s Tropical Medicine and Emerging Infectious Diseases E-Book
by Edward T Ryan, David R Hill, et. al.
Elsevier Health Sciences, 2019

Of the cases involving the CNS, encephalitis, although rare, may give rise to persistent sequelae, but meningitis is thought to be self-limiting (RCGP 1974).

“Infectious Diseases of Humans: Dynamics and Control” by Roy M. Anderson, B. Anderson, Robert M. May
from Infectious Diseases of Humans: Dynamics and Control
by Roy M. Anderson, B. Anderson, Robert M. May
OUP Oxford, 1992

Zika virus is linked to fetal microcephaly and Guillain-Barré syndrome.

“Skills for Midwifery Practice Australia & New Zealand edition” by Sara Bayes, Sally-Ann de-Vitry Smith, Robyn Maude
from Skills for Midwifery Practice Australia & New Zealand edition
by Sara Bayes, Sally-Ann de-Vitry Smith, Robyn Maude
Elsevier Health Sciences APAC, 2018

Studies in mice with immune defects suggest that Zika virus replicates initially in the placenta followed by infection of the fetus, and that viral replication occurs in neural precursor cells, leading to reduced brain size and thinning of the cortex.

“Robbins & Cotran Pathologic Basis of Disease E-Book” by Vinay Kumar, Abul K. Abbas, Jon C. Aster
from Robbins & Cotran Pathologic Basis of Disease E-Book
by Vinay Kumar, Abul K. Abbas, Jon C. Aster
Elsevier Health Sciences, 2020

CDC concludes Zika causes Microcephaly and other birth defects.

“Taylor and Hoyt's Pediatric Ophthalmology and Strabismus E-Book” by Christopher J. Lyons, Scott R. Lambert
from Taylor and Hoyt’s Pediatric Ophthalmology and Strabismus E-Book
by Christopher J. Lyons, Scott R. Lambert
Elsevier Health Sciences, 2016

The disease itself is self-limiting; however, there is an association between Zika infection in pregnancy and fetal malformations.

“Burns' Pediatric Primary Care E-Book” by Dawn Lee Garzon Maaks, Nancy Barber Starr, Margaret A. Brady, Nan M. Gaylord, Martha Driessnack, Karen Duderstadt
from Burns’ Pediatric Primary Care E-Book
by Dawn Lee Garzon Maaks, Nancy Barber Starr, et. al.
Elsevier Health Sciences, 2019

Zika is linked to microcephaly,

“HESI Comprehensive Review for the NCLEX-PN® Examination E-Book” by HESI
from HESI Comprehensive Review for the NCLEX-PN® Examination E-Book
by HESI
Elsevier Health Sciences, 2019

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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52 comments

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  • The volume needs to be up on this. You’re speaking into microphones and I still cant hear you. My volume is up as loud as it can be.

  • Don’t belive anything they say, before anything new gets used for today it will take 17 years. Thats how long it takes for something new to get used and the heatl care updated to that new technique. Capitalism don’t let them.

  • Do an episode on bipolar too, later research has uncovered some really cool things. And it turns out bipolar is waaaaay more complicated then people thought.

  • I was recently diagnosed with Multiple Sclerosis, which is a “Auto-Immune” condition of the brain and spinal cord. On my father’s side I have an Aunt who has been in a state mental hospital most of her life for Schizophrenia a possible “Auto-Immune” condition of the brain.

  • I have Mal de Debarquement Syndrome since July 1, 2018. I also have Hashimoto’s and cervical spine stenosis. I did the experimental treatment at Mount Sinai but it didn’t work. I was triggered by a plane. Can you help people who are swaying and bobbing 24/7?

  • Is there a time and place where schizophrenia incidence was abnormally high? If yes maybe try to see if an overactive immune system could have presented an evolutionary advantage over other individuals under those circumstances.

  • Does this mean that people with allergies are more prone to develop schizophrenia?
    What about the roll of glial cells in the brain?

  • Hello; I wrote a book which includes the topic of schizophrenia with the comorbidity of TBI. My pen name is:

    ☕�� Matthew Aphasia: DEMENTED AmAzON book. Please read and review my book if you have the time. I’d really appreciate honest feedback! Thank you for your time. ��

  • I have Bipolar Disorder, and I also have an autoimmune disorder, called Hashimoto’s Disease, which I inherited from my mother, who also has postpartum depression and Seasonal Affective Disorder. Makes me wonder…

  • I wonder if any food allergies can be related to this as some food allergies can cause long-term inflammation and what seems to be an autoimmune response.

  • Anyone with schizophrenia should research supplementing with Niacin (the kind that causes flushing), and limiting L-Carnitine. Carnitine is in its highest concentration in red meats. Also the amino acid Lysine is converted into Carnitine in the body, so watching that might help too. In my empirical opinion, Carnitine raises dopamine to a dangerous level in a person with schizophrenia and can lead to psychosis.

  • Ces faux je le suis et se que je croit de moi devien biologiquement et metalement donc ces faux vous avez rendu les gens de la foi malade avec cette oenser

  • I was diagnosed with Schizoaffective disorder with depression, severe anxiety, and Asperger’s in 2014 and was on high dose ‘cocktails’ of many different very strong medications for about a year. None of them worked and were making me worse, and I had such a bad reaction to Zoloft that it almost putting me in the ICU and I still have permanent side effects from Seroquel and Risperdal. In 2015 my psychiatrist diagnosed me with multiple drug intolerance and told me there was nothing she could do to help me anymore. My anxiety and hallucinations were getting worse every day, desperate to find a remedy started researching. I read every medical publication and listened to every lecture I could find on anxiety, depression, schizophrenia, and autism disorders, and what I found was astonishing and life changing. I learned that there is a direct connection between the microbiome (the trillions of bactria and fungi and such that live mostly in your gut) and the brain, and when the microbiome is severely out of balance it will manifest as the mental disorders so many people, I included, suffer with.

    I also learned that depression, psychotic, anxiety, and autism medications modulate the microbiome, which alters the communication in the gut-brain axis. A change in diet and removing toxic chemicals from your environment will help more with mental disorders than any medications ever will. It takes an average of around four weeks to modify the microbiome. This is why all these meds take so long to work and also why only about a third of people who take them see any improvement; the other two thirds of people either experience no change in symptoms or end up getting worse, like I did.

    Lookup “Microbial Endocrinology” to learn more about how the bacteria and fungi in your gut talk with your brain.

  • Growing up I used to worry I might develop schizophrenia. Instead I got multiple sclerosis, an auto-immune disease that attacks the brain and spine. I’ve had some minor hallucinations and delusions as a result and I often wondered how different it really was from schizophrenia. Apparently not much.

  • Kudos for the one small step towards scientifically literate reporting at 2:32 (“Whether that’s because inflammation causes schizophrenia or the other way around isn’t clear”) but you forgot the other very likely possibility that neither causes the other, but instead that both inflammation and schizophrenia are caused by an unidentified third factor.

  • Lots of questions First: I’ve heard Schizophrenia and BiPolar disorder compared to a spectrum being part of the same family of diseases. Does this ring true for BiPolar disorder? Second this would make a lot of sense as to why Schizophrenia and possibly other disorders don’t often appear until mid teens to mid 20’s.

  • I read an article in MIT’s magazine saying that it’s because microglia, which sort of “clean up” unused neurons and act like janitors for the brain, are “cleaning up” pathways in the brain that they shouldn’t. They spoke of how the cause was likely genetic. And they spoke about how they couldn’t just remove microglia because, besides the necessary cleaning not being performed, they secrete an enzyme that neuronal tissue can’t function without. It was quite fascinating and has stuck with me for years. I had to have read it around 4 years ago.

  • I wish medical science would stop treating psyche like it isn’t part of the large organ in our heads. If an auto-immune disease can cause my type 1 diabetes, psoriasis and lupus then why couldn’t it do the same to the brain?

  • 1:56 No! STIMULATION! Fluctuations in radical stimulation. Sometimes there, most times not…. I don’t disagree that to some degree it’s in your pedigree, but b’le’me, the phrenie is stimuli….

  • It’s sounds good… Pls provide me your what’sup number because I need of your consultation as my father is suffering from neuro problem

  • This is a little bit of a weird story but hear me out. A little back knowledge to begin, my mother has her bachelors degree in biology, so she is educated to make an intelligent hypothesis. Continuing on, I had an ex bf whose step father suddenly had extreme behavior changes and schizophrenic like symptoms. Well their house was covered in house cat excretions and bodily fluids. One of the cats was really weird and my mom had the idea that the step fathers behavior changes were related to the state of the house because of toxoplasmosis, which is spread through cat feces. Toxoplasmosis can cause psychological symptoms. And that’s how this relates to this video, that schizophrenic symptoms could be caused by an autoimmune response to some bacteria/infection or virus, or parasite.

  • Let us take a different perspective. How about that people who who have a NORMAL reaction to a persistent stressful environment THEN DEVELOPE AUTOIMMUNE ISSUES from the CHRONIC STRESS. There is tons of empirical data NOW available through the decades of research done by DR. VIVETTE GLOVER proving that a chronically stressed pregnant mother to be has high levels of stress hormones that bathe the developing brain of the fetus; this chronic exposure to stress hormones dramatically changes the development of the fetus on multiple levels. Brain development, hormone development, etc. This sets the child up FOR THE REST OF ITS LIFE for hyperactivity, anxiety, depression and of course all the immune problems that result from chronic exposure to inflammatory agents.

  • Thanks to the folks at Mayo in Rochester, I was diagnosed with MADSAM and now being treated with IVIG infusions. The doctors at home we’re baffled due to lack of knowledge on this disorder. Thank you for all your help!!

  • I think is it awesome that we might have a better handle on what might cause schizophrenia and how to help those suffering it.
    Now I am wondering how can you tell a mouse has schizophrenia. It isn’t like they can tell the scientists their symptoms.

  • Been dealing with memories of a person with this condition for about a week. Back in the 60’s and 70’s these things were considered character weaknesses and people were locked up and shunned like this lady I was trying to remember. Those who have this condition today can function in society with the meds and for most sufferers they get along adequately.
    Sadly, when I did remember her name and her brothers name, they had both died within the last 2 years. The lady was never able to live on her own because of this condition. Maybe the insight in this video would have helped her!

  • Woooow! This is my first time checking in on this channel, and Im amazed by the character that is narrating this episode. Very well done and easy to follow!

  • This video is extremely misleading schizophrenia is multifactorial resulting from several causes, some of which you address structural abnormalities and excessive synaptic pruning, but you haven’t mentioned the dopaminergic or serotoninergic hypothesis of schizophrenia that also link in excessive dopaminergic neurotransmission causing excitotoxicity and cell death in brain areas such as the prefrontal cortex (executive function) and the nucleus accumbens (mania/arousal) which would cause the higher inflammatory markers mentioned in the video it would also trigger local immune response due to glutamate and ATP and calcium release from cell death which may worsen the problem but is definitely not the whole picture like this video makes out schizophrenia may be correlated with autoimmune conditions and there may even be causal overlap in the pathological mechanisms but schizophrenia is still and always will be a wide range of neurodegenerative conditions with a common symptomology but an extremely complex aetiology what causes neuron death? Turns out lots of stuff genetics, inflammation, heavy metals, stress, poor diet including hypovitaminosis, lifestyle choices anyone can get it at any time in there life, it’s the end stage of a descent into madness who hasn’t raged out before? Well if you keep going the end result is schizophrenia it takes some longer than others but anyone can get it if they’re pushed hard enough and it doesn’t have a single cause especially not inflammation if it’s correlated then it could well be reverse causality since neurone death causes inflammation therefore developing schizophrenia causes inflammation and probably not the other way around although that’s not to say inflammation can’t worsen schizophrenia it absolutely can and failure to terminate that positive feedback loop may explain somewhat individual susceptibility

  • I have some issue where I start vomiting & don’t stop for sometimes a few days. I get inflammation. Sometimes I mildly hallucinate. One time it was bad. I was in my bed but when i closed my eyes which was most of that time… I would hallucinate that I was in jail or prison & people were telling me we weren’t allowed anything to drink. & if we get caught we get killed. Somehow my senses would come back long enough to take a drink of water. & if my eyes were closed when I drank, it would get worse.. I have stomach & intestinal issues, its amazing how it can affect my mental state.

  • I saw a video about some mental health problems possibly being autoimmune disorders a while ago, most doctors wouldnt consider that in a diagnosis

  • You missed the part where 52% of Schizophrenics have been successfully treated with high doses of B vitamins. Which is an electric wire missing insulation. Also forgot the role of Toxoplasmosis! You know, the parasite anyone can get when encountering cats. Which, not like Egypt, but are everywhere?

  • Antipsychotics modulate the microbiome, which alters the communication in the gut-brain axis. Same goes for antidepressants and antianxiety medications.
    A change in diet and removing toxic chemicals from your environment will help more with mental disorders than any medications ever will.

    It takes an average of around four weeks to modify the microbiome. This is why all these meds take so long to work and also why only about a third of people who take them see any improvement: the other two thirds of people either experience no change in symptoms or end up getting worse.

    Lookup “Microbial Endocrinology”
    to learn more about how the bacteria and fungi in your gut talk with your brain.

  • I think this has merit but if this is true how is it explained that schizophrenia onset is most common in late teens and the twenties. Why a certain age?

  • wow I have schizoaffective disorder and a few year after first episode I started getting rashes and lost hair on the back of my head though my own research I found that these could be auto immune I still have large bald spot hair loss has stop it seem when I am in high stress these auto immune symptoms show more my wonder is if it is a virus in the brain causing it this was my thought even before 2020 I have been called delusional for thinking schizophrenia may be caused from a virus

  • dr wallach the nobel prize nominee a naturopath cures all these problems with hardcore vitamins and minerals, md’s dont have nutritional training,

  • My grandfather exhibited schizophrenia-like behaviors after he got his leg amputated. He was fine before that but after he got discharged he slowly gotten worse. At first, I though it’s because he was depressed because of the lost of his leg but after hearing him say that people are outside our window or after he was talking about war and other figment of his imagination (or maybe distorted memories), it dawned on me that he might have schizophrenia. We did not really took him to a specialist since there isn’t one near us and we don’t have the money to even go see a doctor much more for medication and therapy. Grandpa passed away 4 or 5 years after the amputation. Long story short, if this is true, this explains how he suddenly went from normal to his state in just a few months.

  • “…everyone knows women tend to be hysterical about…” Was that meant to be serious? I’m asking because I’ve been treated as such all my life…and it took 45 years to find out I have celiac disease. Now I’m in excruciating pain & have had to quit working & school. I’ve suffered all my life & no one took me seriously. I sure hope you were joking.

  • Life is in God hands please dont spread misconception and don’t scared to people…people have children….people don’t want their children die…

  • Is inflammation from allergies (for example hay fever) included in the inflammation that may cause schizophrenia? And are allergies an autoimmune disease?

  • This is very interesting to me. I had a client who has psoriasis in addition to schizophrenia and both seemed to flare up at the same time.

  • 4:50 no, no, nope. lab mice have been selectively bred to be more resilient to random drugs by virtue of decades of use. lab mice are essentially their own species now, don’t trust any studies relying on them. I’ll find the video in a minute.

  • I think it might not just be schizophrenia though? My psychiatrist explained to me that inflammation is involved in all mental illnesses.

    Either way, it’s good news that the research is getting so broad. We need them to look in every nook and cranny.

  • This was terribly researched (after looking at the publist okay terribly presented). Yes, schizophrenia and autoimmune is linked. But that’s it. I’m also linked with chocolate, but that doesn’t imply a causal or even meaningful relationship. E.g. how much better was that outcome of NSAIDS+schizophrenia meds? What was measured? And seriously, if you can’t even pronounce microglia right, you’re not supposed to give a science talk. I like this channel but this is ridiculous. Do you just aim for comments ‘I have someone in my family that has an autoimmune disease and it sucks’ (which, btw, yes, it really does!) or actually convey solid information on the research front that people can benefit from?

  • Sychiatry is Seudo Pscience.
    A lot of “new developments” in schizophrenia “research” are brought to light by perpetrators of illegitimate incarceration trying to cover up all the damage their forced drugging and other damaging “treatment” has caused. Harm is the middle word in Psychop harm acology.

  • I’ve been diagnosed with sorgrens, RA, and fibromyalgia. I was misdiagnosed for years under major depression. I live in Florida. Does Mayo accept Humana gold?

  • According to WHO there is no confirmed link between microcephaly in newborns and Zika virus so before you start reporting more bullshit you better check with them first so you all have your story straight.

  • It’s starting to come together now. I remember how a schizophrenic in South Korea contracted COVID from the healthcare staff at his hospital then died from it. He was the first confirmed COVID death in South Korea, about 1 month back

    At the time, it seemed especially peculiar to me that for some reason a schizophrenic would contract COVID and die even though initially COVID doesn’t hit those below 60 as hard in terms of age demographic. The schizophrenic in question was around 52-56 and didn’t show any other known risk factors at the time

    With this new hypothesis, his death due to COVID makes much more sense now

  • My colleague and me University of Vienna; we both hold degrees (she is a teacher and I am a philosopher, was a translator, and musician) and unfortunately experience strangest neurological etc symptoms I have confirmed Lyme disease and coinfections; I/we suspect autoimmunity as well. If you can recomment me /us a neurologist, knowledgaeble on this topics in EUROPE/around AUSTRIA, I would be very grateful. [email protected] gmail.com

  • La foi boost et detruire les nauvais gene epigenetique et delire egal foi si je suis divin dieu grec je suis donc superieure par le mental donc exlloit le delire positivement pour renforcir on devien super humain donc la horde angelique es levolution manupilez les alchimiste son devenu chimere

  • I have it and it sucks balls and i keep losing my mind!! But i have a great immune system i never get sick at all!! But i do throw up blood everyday!!

  • You add up all of those percentage increases in terms of risk factor and it seems like a no brainer causal link… until you realize those numbers add up to less than a doubling of risk, so 2% risk instead of 1%….

  • How about schizoaffective disorder? It has elements of schizophrenia. Plus, it’d make sense since I also suffer a condition which is showing more evident day by day to be Crohn’s disease which is an inflammatory disease of the bowels (still awaiting colonoscopy which has been rightfully delayed thanks to prioritizing covid 19 sufferers).

  • I have a sister with an auto-immune disorder and one with mental health problems similar to schizophrenia. I also had a brother with Aspergers (R.I.P) and I myself have Asperger’s (and depression). Any chance they are all somehow related (the conditions, that is: Smartar*e removing sentence).