NEW YORK — U.S. scientists released a new finding that shows in addition to causing brain abnormalities in developing fetuses, the Zika virus may also damage in adult brain cells.. .
“This is the first study looking at the effect of Zika infection on the adult brain,” Joseph Gleeson, adjunct professor at the Rockefeller University and head of the Laboratory of Pediatric Brain Disease said in a press release. “Based on our findings, getting infected with Zika as an adult may not be as innocuous as people think.”.
Human brains comprised entirely of neural progenitor cells, which eventually become fully formed neurons after entering adulthood. Scientists found out the cells were particularly vulnerable to Zika virus.. .
In an experiment using mice to mimic the effect of Zika infections in humans, the virus attacked neural progenitor cells, which exist primarily in the subventricular zone of the anterior forebrain and subgranular zone of the hippocampus in mice. The two zones are vital for learning and memory. The loss of these cells would subsequently lead to the reduction in brain volume.. .
The study was conducted by the Rockefeller University and La Jolla Institute for Allergy and Immunology and published in the journal Cell Stem Cell.. -- .
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The Zika epidemic started raging in 2015, terrifying the world with images of newborns with terrible birth defects. But one researcher is using brain stem cells to find a drug that could treat or even cure infected people
Using stem cells—like those found in our earliest embryonic selves—scientists have learned to grow miniature brain-like structures, called brain organoids. How similar are organoids to a real human brain, and what can we do with them? So far, scientists have seen brain organoids send signals in coordinated patterns that look somewhat like the brain waves in a fetus. Join a conversation with leading organoid researcher Alysson Muotri to explore how brain organoids might help us study human brain disorders and the very earliest stages of brain development.. Lose yourself in over 650 interactive exhibits exploring perception, art, and science at our adults-only AFTER DARK. Grab your friends and a drink and get immersed in mind-bending experiences and unique, thought-provoking programs.. For more info: https://www.exploratorium/after-dark
On Thursday, May 26, The Kavli Foundation hosted a Google+ Hangout with neuroscientists Arnold Kriegstein, Guo-li Ming and Hongjun Song about Zika’s effects on the brain, plus what it’s like to do emergency research.. Questions: 3:00 What questions first spring to mind about Zika and microcephaly? 5:50 What are human embryonic neural cortical progenitor cells and what do they do? 8:10 What does Zika actually do to these neural progenitor cells? 9:50 Can you describe what “mini-brains” are? 12:20 So when the mini-brains were infected with Zika, what did you see? 14:40 How does genetic microcephaly differ from those caused by Zika? 17:50 Do we know why Zika microcephaly is so severe? 20:10 What ideas do you have that might help to combat the Zika virus? 22:50 What are the urgent questions about Zika and the developing brain? 25:35 Zika is part of a family of viruses, is there anything helpful that we gather form studying like viruses? 27:50 How has the experience studying Zika differed compared to other projects?
This lecture will discuss the virus and its epidemiology and compare it with the dengue fever virus about which much more is known. http://www.gresham.ac.uk/lectures-and-events/the-zika-virus-dengue-and-the-yellow-fever-mosquito. The Zika virus originated in Africa and causes a febrile illness but was little known until it spread within Brazil in 2014. It is now found from Mexico to Paraguay as well as in other parts of the world and has been linked to serious birth defects. The disease shows no signs of abating. There are no drugs or no vaccine, so the method of control is to attack the mosquito. What makes the mosquito (Aedes aegypti) a super efficient transmitter of viruses? and how it might be controlled by the use of genetically modified mosquitoes? The lecture will also discuss the nightmare scenario of the increased range of the mosquito as a result of climate change.. The transcript and downloadable versions of the lecture are available from the Gresham College website: http://www.gresham.ac.uk/lectures-and-events/the-zika-virus-dengue-and-the-yellow-fever-mosquito. Gresham College has been giving free public lectures since 1597. This tradition continues today with all of our five or so public lectures a week being made available for free download from our website. There are currently over 1,900 lectures free to access or download from the website.. Website: http://www.gresham.ac.uk. Twitter: http://twitter.com/GreshamCollege. Facebook: https://www.facebook.com/greshamcollege. Instagram: http://www.instagram.com/greshamcollege
FRIDAY, May 6, 2016 (HealthDay News) The terrible birth defects caused by Zika virus appear to be the result of an immune system response that triggers prenatal brain cell suicide and obstructs. Dennis Thompson, HealthDay News FRIDAY, May 6, 2016 The terrible birth defects caused by Zika virus appear to be the result of an immune system response that triggers prenatal brain cell suicide. Zika Destroys Fetal Brain Cells, Lab Study Finds The terrible birth defects caused by Zika virus appear to be the result of an immune system response that triggers prenatal brain cell suicide and obstructs fetal brain development, a new lab study reports.
Zika Destroys Fetal Brain Cells, Lab Study Finds The terrible birth defects caused by Zika virus appear to be the result of an immune system response that triggers prenatal brain cell suicide and obstructs fetal brain development, a new lab study reports. FRIDAY, May 6, 2016 (HealthDay News) The terrible birth defects caused by Zika virus appear to be the result of an immune system response that triggers prenatal brain cell suicide and obstructs fetal brain development, a new lab study reports. Study Finds Zika Virus Destroys Cells Crucial for Fetal Brain Development 2016-03-07 04:37:20 The spread of the Zika virus has spurred public health concerns that it will become the next viral epidemic. Zika May Infect Fetal Brain Cells, Study Finds March 4, 2016 SEAN DUFFY (CN) – Scientists researching the link between the Zika virus and birth defects have discovered that the virus is able to infect cells similar to the ones involved in brain development, according to a study published Friday. Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly.
In a small proportion of cases, the disease. The terrible birth defects caused by Zika virus appear to be the result of an immune system response that triggers prenatal brain cell suicide and obstructs fetal brain development, a new lab study reports. The virus apparently activates an immune receptor called TLR3, Zika, destroys, fetal, brain, cells, birth, detects 678.
Zika can infect adult brain cells, not just fetal cells, study suggests Illumination of the fluorescent biomarker in green reveals that the adult mouse brain could be infected by Zika in a region.
List of related literature:
Studies in mice with immune defects suggest that Zika virus replicates initially in the placenta followed by infection of the fetus, and that viral replication occurs in neural precursor cells, leading to reduced brain size and thinning of the cortex.
In support of this potential pathogenic mechanism, Zika virus has been cultured from the brain of a fetus with severe brain anomalies after maternal infection at 11 weeks’ gestation.
During April 2016, the Centers for Disease Control and Prevention (CDC) concluded “… that Zika virus is a cause of microcephaly and other severe brain defects”15 Infection with the Zika virus increases the risk of adverse health outcomes; not all infected pregnant females will give birth to infants who have
Zika infection during pregnancy may cause severe birth defects including microcephaly and fetal death, and patients have developed Guillain–Barré syndrome.
Notes from the field: evidence of Zika virus infection in brain and placental tissues from two congenitally infected newborns and two fetal losses – Brazil, 2015.
Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.
So the vaccine is more effective on people that have had the virus previously so how do they know it’s not that they have previously had it that is giving protection and not the vaccine
Oh god. This has the potential to end the entire human race. It’s fascinating how mother nature finds a way to get rid of the most predatory (and wasteful) species on earth…..HUMANS. These mosquitos have existed for millions of years. I doubt modern science will be able to kill these fuckers. Then it’ll get so bad to the point that no one will be able to reproduce……
I can see all the third wave feminist intentionally infecting themselves with zika by flying to Florida and protesting “it’s my right to get Zika, don’t tell us what to do with our body!”
Seriously!! We have the mean wipe those fu*#%ing annoying species off of the face of the earth. I get it that some scientists are worried about the eco system but those thing barely add any contribution. I strongly suggest that we just eradicated them
Zika is the gift that keeps on giving: funny looking babies, tight vaginas for the moms, and now you can forget all about the lies and evil you did in your past. I nominate Zika for a Nobel Prize.
Does anyone find it odd that the insecticide being use directly affects the nervous system in a similar way as Zika? I’m not saying that our government would lie or make up false emergencies in order to take away rights but………
I’m glad I’m poor in a rich country ��.
Not rich in a poor country ��
Probably still got a bit of coronavirus, still it’s not the amount that counts!!
It’s the taking place ��.
All part of the Chinese experience ��
I got RA,
Thought it was because of the cold weather in uk!!! ������
How wrong was I!!!
DEMARDS for me ��
Which scientific journal were these discoveries published in? They never mention it. They just want to sway public opinion through innuendos.
So the vaccine is more effective on people that have had the virus previously so how do they know it’s not that they have previously had it that is giving protection and not the vaccine
Oh god. This has the potential to end the entire human race. It’s fascinating how mother nature finds a way to get rid of the most predatory (and wasteful) species on earth…..HUMANS. These mosquitos have existed for millions of years. I doubt modern science will be able to kill these fuckers. Then it’ll get so bad to the point that no one will be able to reproduce……
I can see all the third wave feminist intentionally infecting themselves with zika by flying to Florida and protesting “it’s my right to get Zika, don’t tell us what to do with our body!”
Seriously!! We have the mean wipe those fu*#%ing annoying species off of the face of the earth. I get it that some scientists are worried about the eco system but those thing barely add any contribution. I strongly suggest that we just eradicated them
Zika is the gift that keeps on giving: funny looking babies, tight vaginas for the moms, and now you can forget all about the lies and evil you did in your past. I nominate Zika for a Nobel Prize.
Does anyone find it odd that the insecticide being use directly affects the nervous system in a similar way as Zika? I’m not saying that our government would lie or make up false emergencies in order to take away rights but………