Zika Causes Prevalent Harm to Fetal Brain

Zika Virus and the Fetal Brain

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www.dailyrxnews.com.
The Zika virus has been in the news a lot lately. As more information becomes available, concerns have increased, and rightfully so..
A study from the University of Helsinki found that the fetus of a pregnant woman infected with the Zika virus developed severe brain abnormalities..
Zika virus is spread by the Aedes mosquito. First discovered in Uganda in the 1940s, the virus began to spread around the world in the early 2000s. Zika caused extensive epidemics in the Pacific areas and since 2015 it has spread through South and Central America.

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Zika Virus Infection Lark Coffey

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Zika Virus Infection Dynamics in Experimentally Infected Mosquitoes and Pregnant Macaques 7th Annual Bay Area Symposium on Viruses

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Virus Watch: Zika Virus and Microcephaly

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Three papers have been published showing that Zika virus can cross the placenta in mice, replicate in the fetus, and cause microcephaly. In this episode I summarize these data and their implications..
Links to papers discussed:.
http://dx.doi.org/10.1016/j.stem.2016.04.017.
http://dx.doi.org/10.1038/nature18296.
http://dx.doi.org/10.1016/j.cell.2016.05.008

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Zika Virus Epidemiology and Congenital Zika

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(Visit: http://www.uctv.tv/) Yvonne (Bonnie) Maldonado, MD, Stanford University Series: “Developmental Disabilities 2017 Update” [Show ID: 32196]

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CDC study reveals lasting impact of Zika virus

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While the threat from the Zika crisis has calmed, the Centers of Disease Control and Prevention released a study last week exploring the effects of the virus on babies born with brain damage from the virus, who are now toddlers. Pam Belluck from The New York Times joins CBSN to discuss the lasting impact of the Zika virus on toddlers.

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Zika Virus: ‘Already, I can see the hallmarks of severe brain damage’

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Dr. Brian Goldman heads to Brazil, where the Zika virus has caused microcephaly in babies. Hear the full documentary on The Current on CBC Radio One: http://cbc.ca/1.3540497..
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How the Zika virus affects an infant’s brain

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Doctors confirmed the link between the Zika virus and microcephaly in April. While the most visible sign of microcephaly is the small size of the head, its actually inside the brain where the most damage occurs. (Whitney Leaming, Julio Negron/The Washington Post)

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“Zika virus can directly kill neural cells as well as alter their differentiation pathway, making the fetal brain smaller by the end of pregnancy,” said senior researcher Dr. Amilcar Tanuri. By Dennis Thompson. HealthDay Reporter. MONDAY, Oct.

3, 2016 (HealthDay News) A new study shows that Zika virus causes so much varied damage throughout the fetal brain that researchers are suggesting the term “congenital Zika syndrome” be used to describe the numerous birth defects. Microcephaly an underdeveloped skull and brain is the hallmark birth defect caused by Zika, which. “Zika virus can directly kill neural cells as well as alter their differentiation pathway, making the fetal brain smaller by the end of pregnancy,” said senior researcher Dr.

Amilcar Tanuri. Microcephaly—an underdeveloped skull and brain—is the hallmark birth defect caused by Zika, which is mainly transmitted by mosquito bite. But the study of 11 Zika-infected infants in Brazil—the epicenter of the Zika epidemic—found that microcephaly is. “Zika virus can directly kill neural cells as well as alter their differentiation pathway, making the fetal brain smaller by the end of pregnancy,” said senior researcher Dr.

Amilcar Tanuri. He’s head of the Molecular Virology Laboratory at the Federal University of Rio de Janeiro in Brazil. That’s how microcephaly develops, he explained. “Zika virus can directly kill neural cells as well as alter their differentiation pathway, making the fetal brain smaller by the end of pregnancy,” said senior researcher Dr.

Amilcar Tanuri. He’s head of the Molecular Virology Laboratory at the Federal University of Rio de Janeiro in Brazil. That’s how microcephaly develops, he explained. Researchers are suggesting the term “congenital Zika syndrome” to describe many birth disabilities in the fetal brain, according to a new study.

A particular trait caused by Zika is microcephaly, which is an underdeveloped brain and skull. Researchers studied 11 Zika-infected babies in Brazil, which is the epicenter of the epidemic. A study has found that viruses related to Zika, such as West Nile, can cross the placenta in mice and cause fetal brain damage and death.

Two viruses closely related to Zika – West Nile and Powassan – can spread from an infected pregnant mouse to her fetuses, causing brain damage and fetal death, according to a new study from Washington. One of the frightening side-effects of Zika virus infection in pregnant women is the risk of fetal microcephaly, in which babies are born with abnormally small brains. The multidisciplinary collaboration of Yale scientists revealed that Zika virus kills stem cells in the brain and disrupts the process of creating brain cells.

A fetus that was aborted weeks after the mother was infected with Zika provides striking evidence that the virus causes fetal brain abnormalities, researchers say.

List of related literature:

Signs and Symptoms Zika infection during pregnancy can cause the birth defect microcephaly, which is caused by incomplete brain development and other severe fetal brain defects.
from Immunology & Serology in Laboratory Medicine E-Book by Mary Louise Turgeon Elsevier Health Sciences, 2017
When pregnant women are infected with Zika virus for the first time in pregnancy, it may cause severe damage to the fetus, in particular causing microcephaly, ocular abnormalities, hearing loss, and arthrogryposis.
from Neonatology at a Glance by Tom Lissauer, Avroy A. Fanaroff, et. al. Wiley, 2020
Zika infection during pregnancy may cause severe birth defects including microcephaly and fetal death, and patients have developed Guillain–Barré syndrome.
from Habif’ Clinical Dermatology E-Book by James G. H. Dinulos Elsevier Health Sciences, 2019
Though not typically life-threatening, Zika is known to cause microcephaly, an incurable form of brain damage in newborns whose mothers have been infected with the virus during pregnancy.
from Building a Resilient Tomorrow: How to Prepare for the Coming Climate Disruption by Alice C. Hill, Leonardo Martinez-Diaz Oxford University Press, Incorporated, 2019
During April 2016, the Centers for Disease Control and Prevention (CDC) concluded “… that Zika virus is a cause of microcephaly and other severe brain defects”15 Infection with the Zika virus increases the risk of adverse health outcomes; not all infected pregnant females will give birth to infants who have
from Epidemiology 101 by Friis Jones & Bartlett Learning, 2017
Zika virus can be spread from a pregnant woman to her fetus and has been linked to a serious birth defect of the brain called microcephaly (Fig. 18.13) in babies of mothers who had Zika virus while pregnant.
from Modern Dental Assisting E-Book by Doni L. Bird, Debbie S. Robinson Elsevier Health Sciences, 2020
While it can’t be definitive proof, it may present the most compelling evidence to date that congenital brain malformations associated with Zika virus infection in pregnancy are a consequence of viral replication in the fetal brain.”
from A Terrible Thing to Waste: Environmental Racism and Its Assault on the American Mind by Harriet A. Washington Little, Brown, 2019
Zika fever in itself is of no serious hazard to people; however, the Zika virus can cause a serious hereditary deformity (microcephaly) in developing fetuses.
from Human-Insect Interactions by Sergey Govorushko CRC Press, 2018
Zika infection during pregnancy can cause microcephaly and fetal brain defects, and there has been an increased incidence of Guillain-Barré syndrome in persons following Zika infection.
from The Brigham Intensive Review of Internal Medicine E-Book by Ajay K. Singh, Joseph Loscalzo Elsevier Health Sciences, 2017
However, a Zika virus infection during pregnancy can have a devastating effect on a fetus, ruining any chance to have its brain develop normally, as well as sometimes also deforming limbs and causing blindness and deafness.
from Medical Sociology by William C. Cockerham Taylor & Francis, 2017