Your Mind on Oestrogen

 

How Does Estrogen Affect Brain Function?

Video taken from the channel: EmpowHER


 

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365 Estrogen, Progesterone, Testosterone and Mood

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The brain and ovarian hormones | Marwa Azab | TEDxMontrealWomen

Video taken from the channel: TEDx Talks


 

Estrogen shown to have anti-aging effect on the brain

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Estrogen and brain function Presented by Felice Gersh, M.D.

Video taken from the channel: Pure Encapsulations


 

How to Boost Your Estrogen Levels through Food

Video taken from the channel: The Doctors


Estrogen, as you know all too well these days, does a lot of good things for your body and your mood. Maybe you didn’t know that it also does a lot of good things for your brain. “In preclinical studies, estrogen was shown to improve energy production, reduce oxidative stress, increase brain cell survival during damage, enhance the release of protective chemicals, and improve memory,” according. Some of estrogen’s effects in the brain include: Increasing serotonin, and the number of serotonin receptors in the brain Changing how endorphins, the “feel-good” chemicals in the brain, are made.

Estrogen is active in the brain as well, and is involved in regulating learning, memory, and mood. Recent studies have shown that when the brain is at risk, such as during a stroke or traumatic. Your Brain on Estrogen. Estrogen, as you know all too well these days, does a lot of good things for your body and your mood. Maybe you didn’t know that it also does a lot of good things for your brain. “In preclinical studies, estrogen was shown to improve energy production, reduce oxidative stress, increase brain cell survival during damage, enhance the release of protective chemicals, and improve.

Your Brain on Estrogen Estrogen stimulates the growth of neurons, and even repairs damaged neurons. Some of the well documented effects of estrogen on the human brain include: protection from amyloid protein (Alzheimer’s) and injury due. Estrogen acts on receptors found throughout the body, in fat, on ovaries and in muscle. But when it comes to the hormone’s influence on metabolism, Clegg suspected receptors in the brain. High estrogen levels over time can contribute to functional or subclinical hypothyroidism which decreases GABA release in the developing brain.

GABA is a neurotransmitter with a calming effect. This can prime our brain to fire repetitive worry and anxiety circuits over and over again. Estrogen acts on receptors found throughout the body, in fat, on ovaries and in muscle. But when it comes to the hormone’s influence on metabolism, Clegg suspected receptors in the brain. The brain relies solely on blood flow as a source of energy to function and blood vessels make up around one third of the brain.

Estrogen is known to increase cerebral perfusion by binding to. “I love this book! You will look at taking hormones in an entirely new way after reading This is Your Brain on Birth Control.A must read for men and women.” —Louann Brizendine M.D. author of The Female Brain and The Male Brain “This is an urgently needed book that every woman should read.

List of related literature:

However, a-fetoprotein is bypassed in the male brain because circulating testosterone is converted intraneuronally into estrogen by the enzyme aromatase, thus enabling estrogen to defemininize (or masculinize) the male brain, which is mediated through estrogen receptors.

“Stress Science: Neuroendocrinology” by George Fink
from Stress Science: Neuroendocrinology
by George Fink
Elsevier Science, 2010

Each hormone binds to estradiol, androgen, and aromatase receptors that are located in brain regions associated with learning and memory, notably, the hippocampus, amygdala, and prefrontal cortex [1].

“Handbook of Medical Neuropsychology: Applications of Cognitive Neuroscience” by Carol L. Armstrong, Lisa A. Morrow
from Handbook of Medical Neuropsychology: Applications of Cognitive Neuroscience
by Carol L. Armstrong, Lisa A. Morrow
Springer International Publishing, 2019

In other tissues, such as adipose tissue and parts of the brain, testosterone is converted by aromatase to the estrogen, estradiol.

“Doping in Sports” by Detlef Thieme, Peter Hemmersbach
from Doping in Sports
by Detlef Thieme, Peter Hemmersbach
Springer Berlin Heidelberg, 2009

In the brain, the estrogen receptors in particular are heavily concentrated in the cortex and in the limbic system areas.

“Screaming to be Heard: Hormonal Connections Women Suspect... and Doctors Still Ignore” by D. Lee D. Vliet
from Screaming to be Heard: Hormonal Connections Women Suspect… and Doctors Still Ignore
by D. Lee D. Vliet
M. Evans, 2005

It is actually estrogen that makes a brain male.

“Wired for Intimacy: How Pornography Hijacks the Male Brain” by William M. Struthers
from Wired for Intimacy: How Pornography Hijacks the Male Brain
by William M. Struthers
ReadHowYouWant.com, Limited, 2010

clear, but brain areas with high aromatase activity (which thus can convert testosterone to estradiol) and androgen receptors in the nonhuman primate brain include the hypothalamus, amygdala, prefrontal visual, and somatosensory cortices.

“Kaplan and Sadock's Study Guide and Self-examination Review in Psychiatry” by Benjamin J. Sadock, Virginia A. Sadock, Ze'ev Levin
from Kaplan and Sadock’s Study Guide and Self-examination Review in Psychiatry
by Benjamin J. Sadock, Virginia A. Sadock, Ze’ev Levin
Wolters Kluwer Health / Lippincott Williams & Wilkins, 2007

Estrogen and progesterone, hormones produced chiefly by the ovaries, feminize counterpart sites in the female brain.

“The Truth about Homosexuality: The Cry of the Faithful” by John Francis Harvey
from The Truth about Homosexuality: The Cry of the Faithful
by John Francis Harvey
Ignatius Press, 1996

In females, estrogen is excluded from the brain during early development and therefore the brain is configured in a female­typical form in the absence of any sex hormone activity.

“Principles of Neurobiology” by Liqun Luo
from Principles of Neurobiology
by Liqun Luo
CRC Press, 2015

As testosterone affects the entire body (often by enlargening, such accepted facts such as, men have bigger hearts, lungs, liver etc) the brain is also affected by this “sexual” advancement, the enzyme aromatase converts testosterone into estrogen that is responsible for “masculinization” of the brain in a male fetus.

“Health & Drugs: Disease, Prescription & Medication” by Nicolae Sfetcu
from Health & Drugs: Disease, Prescription & Medication
by Nicolae Sfetcu
Nicolae Sfetcu, 2014

There is good evidence that, in organizing the brain in a male direction, testosterone is actually converted by the enzyme aromatase (in the brain itself) to estradiol, so it is actually a female sex hormone that masculinizes the male brain.

“Human Reproductive Biology” by Richard E. Jones, Kristin H Lopez
from Human Reproductive Biology
by Richard E. Jones, Kristin H Lopez
Elsevier Science, 2013

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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26 comments

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  • It is hard to find a good lecture that covers mood and hormones. This is perfect. So comprehensive and insightful. Thank you for making this and sharing it!!!

  • Wow. No wonder diseases like cancer is on the rise. Capitalism and excessive social media influence have us comparing ourselves to unrealistic beauty, body and other society imposed standards in various fields. As a result always the feeling of being not good enough. Stress and depression has become the biggest epidemic of modern world.

  • I am 19 years old and I have been diagnosed with poly cystic ovaries and my gynecologist has given me some hormonal pills which is likely to be taken for one year, Should I continue with those pills?

  • i have febroids and cysts in my uterus ;!!!!
    my life is up side down
    im having all kind of symptoms!!!
    from back pain to legs to heartburns to constipation
    to kydney
    its really effecting my life
    and yet doctors dont care much!!!
    and im more and more depressed!!!
    memorie yes i agree ; and irritability hight level makes everything worst!!

  • Wow… She’s really got the point. I was diagnosed with cyst and had to be operated before that I was fine and have a healthy life but when I let stress and unhealthy lifestyle into my life that’s when it’s getting bigger. Our mind is really can become a time bomb. I take the challenge, I need to get to know my self better. May God always protect us all. Amen.

  • Marwa, this was amazing!!!! I have recently been diagnosed with a hormone imbalance, after seeing 3 doctors, two of which said it was “just pms” and hormones couldn’t be read. My FSH and LH levels are all over the place, and I have a treatment plan. I’m also now working with my body and learning to understand it more. I’m incorporating more vegetables into my body, probiotics, and ensuring I get enough sleep! Thank you for this talk though, it highlighted just how sensitive your hormones can be to other parts of your body and it’s not just always a psychological problem.

  • Most appreciated talk! I went through a horrible menopause, I wasn’t prepared for the psychological along with physical changes I experienced because, no one talks about it enough to help prepare women for what we may experience and how to cope. I found it easier to stop socializing, my life became calmer without the drama of others, but isolationism can’t be the answer.

  • I suffered from debilitating anxiety until menopause almost immediately took it away. I still had problems but no more crippling anxiety. Imagine that! Now I have learned that overactive bladder is associated with psychological symptoms too. Hmmm

  • I am pcod woman i got married for five years I cannot concieve I am worried about pregnancy please guide me my period are regular I am not over weight but my age 40 please guide me

  • I take omega 3 now and flax seeds at dinner time. I put flax seeds in both meals. I love apricots and olives and cook everything in olive oil and try to eat sardines and salmon more. I notice my body is getting it’s curvy and vulmptous look back that it had in my early 30s. ��

  • Serotonin causes anxiety? TOO little serotonin causes anxiety and mood disorders. The only way that can happen is a rare condition named serotonin syndrome, by too much antidepressants or combination of medications and substances.

  • Husbands are the reason of our stress but we cannot eliminate them cause they are essential to the reproductive process… This is a very difficult equation

  • Medicine currently pays lip service to the mind body connection, but if you are ill and also suffer from depression or anxiety (common when someone has a life changing illness…duh!), then they just discount you completely. So to get treatment, we are forced to hide the psych stuff. Those of us with depression and anxiety with chronic pain and illness die on average TEN YEARS sooner than a sick person without psychiatric illness. This is due only in small part to increased suicides. It is mostly true (and even more so among women) that the medical community dismisses and undertreats and fails to diagnose illnesses that eventually lead to death. Combine that with the fact that women often present with nebulous atypical symptoms for things like myocardial infarction (and so are sent home after being cavalierly diagnosed as having a panic attack—which goes in the record too; meaning that if the patient presents again, due diligence to diagnose Can fail to take place based on bias from the previous note. Additionally, women (particularly young women and even more so for minority women or disabled women) with a psychological diagnosis (regardless of how long ago it was diagnosed, how it might fit today, and how severe the condition is) are not seem as reliable reporters of their own symptoms by medical professionals, and are dismissed out of hand. A man with the same symptoms tends to receive far more diagnostic testing and follow up, and those symptoms are seen as more urgent than their female counterparts with the same complaints. For myself, I learned to go to completely different systems for psych vs physical care, and I got married to a man who knew how to advocate for me so I could get better care. Should it be that way? No. But it is the world we live in. I am very knowledgeable about my conditions and well educated with advanced degrees overall, but that doesn’t matter to a lot of doctors. All they see is trouble making, frequent flying, crazy, know-it-all lady that just wants lots of drugs (since I always go to the same hospital, that would be a pretty inefficient way of drug seeking, especially when my doctor is calling ahead and I’m carrying a letter from him. I invite doctors to call my pharmacist and check my state database report regarding controlled symptoms that have been filled; and also to do a toxicology screen if they feel the need before treating me. In other words, my mission is to do everything I can to help a doctor feel comfortable prescribing the meds I need, because I DO get the pressure they are under now. So yeah—-same doctors, same hospitals, physician note and short record (including a palliative care declaration), same pharmacy, there with a family member, no criminal history of any kind, a grade school teacher,etc…all of this adds up to….: NOT THE PROFILE OF A JUNKIE WHO IS DRUG SEEKING. Well, not drug seeking in the sense many people want to believe…just; you know, to feel HUMAN again!����‍♀️

  • Bravo! “The more you learn about you, the better you will emerge”.:) and what she said “you are truely the expert for you, you are the best for you”, I’ve never heard medical professional share my lay person’s belief.:) powerful stuff!

  • Xeno(?) estrogens, hand creams, stress, constipation.
    Keep a diary…?

    She apparently is the only solution, because other Drs don’t know, and its all been a big secret. No!

    This is NOT an amazing talk because it reveals nothing, or at best, it reveals very little.

    The best thing she said is she states ‘you are the expert on you’.

    Women have, for decades, been told it’s their hormones. No!

    Drs don’t routinely test hormones, and when they do test, she says, the test isn’t good enough! So, go to her, the all knowing expert, because she seems to have the answers? No!

    How does anything she say come through as helpful or as a solution, and warrant all the accolades she is receiving here?

    Our female bodies are extraordinary, and we deserve help, but this talk, to my way of thinking, is not a solution and is mostly an ad for her. There are more solutions. She does not explore, with the women in the audience, options.

  • I just wanted to get more info about eostrogen production and boom! * my mind has been blown! (in a very good meaning):D *

    Best TEDx Talk ever!

  • I have been experiencing major acnes, hair loss, acnes in my back, hormonal scars on my face and so many more. i went to the doctor and he prescribed some hormonal pills to balance my progesterone level as he noticed my body is producing testosterone at a disproportionate level. The pill actually changed nothing. I believe my state of mind truly changed everything as i was being more positive and less stressed out my hair loss and acne diminished at a remarkable level. One year later i find this talk, Dr Marwa you are amazing!! whatever she said is entirely true, the main problem is stress and we as women need to get a grip of it since it manifests in such a way that is drastic to us. May we all find way through our hormonal imbalance.

  • Isn’t pregnenolone-steal an outdated myth? Things aren’t as simplistic as “cortisol stealing progesterone production”.. I get the general idea but also, as we can both agree, the body is ever complex.

  • Dr. Marwa you’re truly a beautiful human being and a gift to the world! May you and your family continue to be blessed! So proud of you…

  • Thank you so much Dr.Maria for bring this critical topic to the forefront. It is so true that the we need holistic approach to health. Thank you so much

  • See Alisa Vitti to fix hormones through food!! Seed cycling, etc Woman Code, her book and MyFLO app.
    Separately Femometer app offers advice and hormone tracking to help regulate cycles for decent prices!!

  • Destress, detox, eat balanced and healthy, get enough sleep and meditate. This will heal your body and mind. It’s simple actually. Come out of the hamster wheel.

  • Mashallallah, what a wonderful talk. Love seeing a brilliant Muslim doctor help teach people the truth. Ma Sha Allah May Allah keep you safe and healthy for very long time to teach more.

  • Am having PCOD and am thankful to me that am putting efforts to reverse this and balancing my hormones in natural way….this is a great motivation for me and jas encouraged me more to enjoy my journey of reversing PCOD. But,i have constant headache if anyone can give any solution i will be more than happy to hear that……i have all those symptoms thinning hair,facial hair,fatigue 24×7,irregular cycles but i have jotted dowm courage to overcome this.

  • Women store guilt in the hips/pelvis. Dr Gabor Mate is a resource for understanding the truth about human health. Check out his many talks/books if you thought this talk was interesting.

  • @CatFlashBlue Hi great question. Unfortunately, I don’t have a lot of space and can’t share resources with you here, but feel free to log onto our EmpowHER website to ask a health question to our guides, or learn more about other health conditions.

    Best,