Your Mind on Oestrogen

 

How Does Estrogen Affect Brain Function?

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365 Estrogen, Progesterone, Testosterone and Mood

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The brain and ovarian hormones | Marwa Azab | TEDxMontrealWomen

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Estrogen shown to have anti-aging effect on the brain

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Estrogen and brain function Presented by Felice Gersh, M.D.

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Estrogen, as you know all too well these days, does a lot of good things for your body and your mood. Maybe you didn’t know that it also does a lot of good things for your brain. “In preclinical studies, estrogen was shown to improve energy production, reduce oxidative stress, increase brain cell survival during damage, enhance the release of protective chemicals, and improve memory,” according. Some of estrogen’s effects in the brain include: Increasing serotonin, and the number of serotonin receptors in the brain Changing how endorphins, the “feel-good” chemicals in the brain, are made.

Estrogen is active in the brain as well, and is involved in regulating learning, memory, and mood. Recent studies have shown that when the brain is at risk, such as during a stroke or traumatic. Your Brain on Estrogen. Estrogen, as you know all too well these days, does a lot of good things for your body and your mood. Maybe you didn’t know that it also does a lot of good things for your brain. “In preclinical studies, estrogen was shown to improve energy production, reduce oxidative stress, increase brain cell survival during damage, enhance the release of protective chemicals, and improve.

Your Brain on Estrogen Estrogen stimulates the growth of neurons, and even repairs damaged neurons. Some of the well documented effects of estrogen on the human brain include: protection from amyloid protein (Alzheimer’s) and injury due. Estrogen acts on receptors found throughout the body, in fat, on ovaries and in muscle. But when it comes to the hormone’s influence on metabolism, Clegg suspected receptors in the brain. High estrogen levels over time can contribute to functional or subclinical hypothyroidism which decreases GABA release in the developing brain.

GABA is a neurotransmitter with a calming effect. This can prime our brain to fire repetitive worry and anxiety circuits over and over again. Estrogen acts on receptors found throughout the body, in fat, on ovaries and in muscle. But when it comes to the hormone’s influence on metabolism, Clegg suspected receptors in the brain. The brain relies solely on blood flow as a source of energy to function and blood vessels make up around one third of the brain.

Estrogen is known to increase cerebral perfusion by binding to. “I love this book! You will look at taking hormones in an entirely new way after reading This is Your Brain on Birth Control.A must read for men and women.” —Louann Brizendine M.D. author of The Female Brain and The Male Brain “This is an urgently needed book that every woman should read.

List of related literature:

However, a-fetoprotein is bypassed in the male brain because circulating testosterone is converted intraneuronally into estrogen by the enzyme aromatase, thus enabling estrogen to defemininize (or masculinize) the male brain, which is mediated through estrogen receptors.

“Stress Science: Neuroendocrinology” by George Fink
from Stress Science: Neuroendocrinology
by George Fink
Elsevier Science, 2010

Each hormone binds to estradiol, androgen, and aromatase receptors that are located in brain regions associated with learning and memory, notably, the hippocampus, amygdala, and prefrontal cortex [1].

“Handbook of Medical Neuropsychology: Applications of Cognitive Neuroscience” by Carol L. Armstrong, Lisa A. Morrow
from Handbook of Medical Neuropsychology: Applications of Cognitive Neuroscience
by Carol L. Armstrong, Lisa A. Morrow
Springer International Publishing, 2019

In other tissues, such as adipose tissue and parts of the brain, testosterone is converted by aromatase to the estrogen, estradiol.

“Doping in Sports” by Detlef Thieme, Peter Hemmersbach
from Doping in Sports
by Detlef Thieme, Peter Hemmersbach
Springer Berlin Heidelberg, 2009

In the brain, the estrogen receptors in particular are heavily concentrated in the cortex and in the limbic system areas.

“Screaming to be Heard: Hormonal Connections Women Suspect... and Doctors Still Ignore” by D. Lee D. Vliet
from Screaming to be Heard: Hormonal Connections Women Suspect… and Doctors Still Ignore
by D. Lee D. Vliet
M. Evans, 2005

It is actually estrogen that makes a brain male.

“Wired for Intimacy: How Pornography Hijacks the Male Brain” by William M. Struthers
from Wired for Intimacy: How Pornography Hijacks the Male Brain
by William M. Struthers
ReadHowYouWant.com, Limited, 2010

clear, but brain areas with high aromatase activity (which thus can convert testosterone to estradiol) and androgen receptors in the nonhuman primate brain include the hypothalamus, amygdala, prefrontal visual, and somatosensory cortices.

“Kaplan and Sadock's Study Guide and Self-examination Review in Psychiatry” by Benjamin J. Sadock, Virginia A. Sadock, Ze'ev Levin
from Kaplan and Sadock’s Study Guide and Self-examination Review in Psychiatry
by Benjamin J. Sadock, Virginia A. Sadock, Ze’ev Levin
Wolters Kluwer Health / Lippincott Williams & Wilkins, 2007

Estrogen and progesterone, hormones produced chiefly by the ovaries, feminize counterpart sites in the female brain.

“The Truth about Homosexuality: The Cry of the Faithful” by John Francis Harvey
from The Truth about Homosexuality: The Cry of the Faithful
by John Francis Harvey
Ignatius Press, 1996

In females, estrogen is excluded from the brain during early development and therefore the brain is configured in a female­typical form in the absence of any sex hormone activity.

“Principles of Neurobiology” by Liqun Luo
from Principles of Neurobiology
by Liqun Luo
CRC Press, 2015

As testosterone affects the entire body (often by enlargening, such accepted facts such as, men have bigger hearts, lungs, liver etc) the brain is also affected by this “sexual” advancement, the enzyme aromatase converts testosterone into estrogen that is responsible for “masculinization” of the brain in a male fetus.

“Health & Drugs: Disease, Prescription & Medication” by Nicolae Sfetcu
from Health & Drugs: Disease, Prescription & Medication
by Nicolae Sfetcu
Nicolae Sfetcu, 2014

There is good evidence that, in organizing the brain in a male direction, testosterone is actually converted by the enzyme aromatase (in the brain itself) to estradiol, so it is actually a female sex hormone that masculinizes the male brain.

“Human Reproductive Biology” by Richard E. Jones, Kristin H Lopez
from Human Reproductive Biology
by Richard E. Jones, Kristin H Lopez
Elsevier Science, 2013

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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7 comments

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  • It is hard to find a good lecture that covers mood and hormones. This is perfect. So comprehensive and insightful. Thank you for making this and sharing it!!!

  • Wow. No wonder diseases like cancer is on the rise. Capitalism and excessive social media influence have us comparing ourselves to unrealistic beauty, body and other society imposed standards in various fields. As a result always the feeling of being not good enough. Stress and depression has become the biggest epidemic of modern world.

  • I am 19 years old and I have been diagnosed with poly cystic ovaries and my gynecologist has given me some hormonal pills which is likely to be taken for one year, Should I continue with those pills?

  • i have febroids and cysts in my uterus ;!!!!
    my life is up side down
    im having all kind of symptoms!!!
    from back pain to legs to heartburns to constipation
    to kydney
    its really effecting my life
    and yet doctors dont care much!!!
    and im more and more depressed!!!
    memorie yes i agree ; and irritability hight level makes everything worst!!

  • Wow… She’s really got the point. I was diagnosed with cyst and had to be operated before that I was fine and have a healthy life but when I let stress and unhealthy lifestyle into my life that’s when it’s getting bigger. Our mind is really can become a time bomb. I take the challenge, I need to get to know my self better. May God always protect us all. Amen.

  • Marwa, this was amazing!!!! I have recently been diagnosed with a hormone imbalance, after seeing 3 doctors, two of which said it was “just pms” and hormones couldn’t be read. My FSH and LH levels are all over the place, and I have a treatment plan. I’m also now working with my body and learning to understand it more. I’m incorporating more vegetables into my body, probiotics, and ensuring I get enough sleep! Thank you for this talk though, it highlighted just how sensitive your hormones can be to other parts of your body and it’s not just always a psychological problem.

  • Most appreciated talk! I went through a horrible menopause, I wasn’t prepared for the psychological along with physical changes I experienced because, no one talks about it enough to help prepare women for what we may experience and how to cope. I found it easier to stop socializing, my life became calmer without the drama of others, but isolationism can’t be the answer.