Two Studies Find Routine Mammography Saves Lives

 

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WEDNESDAY, March 21 (HealthDay News) Two long-term studies from the Netherlands suggest that routine mammography screening does save women’s lives. One of the longest national breast cancer screening programs in the world led to a significant drop in deaths and caused limited harm, such as false-positive results and over-diagnosis, according to one of the new studies. WEDNESDAY, March 21 (HealthDay News) Two long-term studies from the Netherlands suggest that routine mammography screening does save women’s lives. One of the longest national breast cancer screening programs in the world led to a significant drop in deaths and caused limited harm, such as false-positive results and over-diagnosis, according to one of the new studies.

Two Studies Find Routine Mammography Saves Lives. Decades-long look at Dutch screening program finds benefit, even as treatments got better. Please note: This article was published more than one year ago. The facts and conclusions presented may have since changed and may no longer be accurate. And “More information” links may no longer work.

Mammography has helped reduce breast cancer mortality in the U.S. by nearly 40% since 1990. 3 out of 4 3/4 of women diagnosed with breast cancer have no family history of the disease and are not considered high risk. 1 in 6. Kate Kelland, Health, Science Correspondent 4 Min Read LONDON (Reuters) Regular mammographic screening for breast cancer saves the lives of two women. The research, involving more than 50,000 breast cancer patients, found that those who took part in a breast cancer screening program had a 60 percent lower risk of.

Breast cancer screening guidelines have been the topic of debate over the past year. One study suggested routine mammograms can save lives for women over 40. Another found that mammography only led to a 10 percent reduction in mortality.

Those types of studies have shown that women who undergo mammography screening have a lower risk of dying from breast cancer, Wender said. The following year, the New England Journal of Medicine published a study by HSPH visiting scientist and Oslo University Hospital surgeon Mette Kalager and colleagues that examined Norwegian mammography data and concluded that for each life saved by mammography screening, between 5 and 15 women would be diagnosed and treated for a cancer that would not have harmed them. The recent Canadian study, involving 90,000 women followed over 25 years in a randomized trial, found that efforts to find breast cancers before they could be felt as a lump in the breast, using screening mammography, did not lead to lower death rates for average-risk women in.

List of related literature:

You don’t have to be a rocket scientist to figure out that this study reconfirms that mammography saves lives.

“Breast Cancer For Dummies” by Ronit Elk, Monica Morrow
from Breast Cancer For Dummies
by Ronit Elk, Monica Morrow
Wiley, 2011

D. Mammography should be performed to identify other areas of involvement.

“The Washington Manual of Surgery” by Mary E. Klingensmith, Abdulhameed Aziz, Ankit Bharat, Amy C. Fox, Matthew R. Porembka
from The Washington Manual of Surgery
by Mary E. Klingensmith, Abdulhameed Aziz, et. al.
Wolters Kluwer Health, 2012

None of the studies (including the Canadian study) showed that mammography led to a reduction in death for younger women.

“Overdiagnosed: Making People Sick in the Pursuit of Health” by H. Gilbert Welch, Lisa Schwartz, Steve Woloshin
from Overdiagnosed: Making People Sick in the Pursuit of Health
by H. Gilbert Welch, Lisa Schwartz, Steve Woloshin
Beacon Press, 2011

However, in a recent meta-analysis of trials and case—control studies, no difference was found in mortality reduction between studies that offered both examination and mammography and those that offered mammography alone.

“Primary Care Medicine: Office Evaluation and Management of the Adult Patient” by Allan H. Goroll, Albert G. Mulley
from Primary Care Medicine: Office Evaluation and Management of the Adult Patient
by Allan H. Goroll, Albert G. Mulley
Wolters Kluwer Health/Lippincott Williams & Wilkins, 2009

The acceptability of mammography has been confirmed in numerous studies.

“Merrill's Atlas of Radiographic Positioning and Procedures E-Book: Volume 2” by Bruce W. Long, Jeannean Hall Rollins, Barbara J. Smith
from Merrill’s Atlas of Radiographic Positioning and Procedures E-Book: Volume 2
by Bruce W. Long, Jeannean Hall Rollins, Barbara J. Smith
Elsevier Health Sciences, 2018

At the same time, other statisticians, reviewing the same set of randomized trials, had chosen to give priority to the exact opposite studies—those that had found mammography to be a lifesaver.

“The Breast Cancer Wars: Hope, Fear, and the Pursuit of a Cure in Twentieth-Century America” by Barron H. Lerner
from The Breast Cancer Wars: Hope, Fear, and the Pursuit of a Cure in Twentieth-Century America
by Barron H. Lerner
Oxford University Press, 2001

Ongoing research is required to determine the benefit of mammography in this population.

“Comprehensive Care of the Transgender Patient E-Book” by Cecile A Ferrando
from Comprehensive Care of the Transgender Patient E-Book
by Cecile A Ferrando
Elsevier Health Sciences, 2019

Indeed there is a fair amount of data to suggest that routine clinical follow-up makes no difference to the detection of recurrence or to the subsequent outcome, and it is likely that mammography alone is all that is required if combined with open access to clinic for any concerns the patient might have.

“Clinical Surgery E-Book: With STUDENT CONSULT Online Access” by Michael M. Henry, Jeremy N. Thompson, Asif Chaudry
from Clinical Surgery E-Book: With STUDENT CONSULT Online Access
by Michael M. Henry, Jeremy N. Thompson, Asif Chaudry
Elsevier Health Sciences, 2012

Mammography not only lowers mortality, but it also decreases morbidity because less radical surgery is necessary for smaller lesions.

“Clinical Gynecologic Endocrinology and Infertility” by Marc A. Fritz, Leon Speroff
from Clinical Gynecologic Endocrinology and Infertility
by Marc A. Fritz, Leon Speroff
Wolters Kluwer Health/Lippincott Williams & Wilkins, 2011

They reported that five of the seven studies were too flawed to be credible, and the remaining two studies showed that mammography did not save, or even prolong, lives.

“Health Promotion and Aging: Practical Applications for Health Professionals” by David Haber, PhD
from Health Promotion and Aging: Practical Applications for Health Professionals
by David Haber, PhD
Springer Publishing Company, 2013

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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4 comments

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  • At what age did you start your annual mammograms?

    The world’s leader in breast mammography Dr. Laszlo Tabar discusses how valuable routine screening & mammography can be. 

    Please get make it a point to go to your routine screening.

    #NationalMammographyDay

  • Bayes’ Theorem and Breast Cancer Screening with mammography.

    Please update and re-upload this excellent informative video using current scientific data.

    Sensitivity and Specificity of screening digital mammography in a recent extensive Norwegian clinical trial were 54.1% and 94.2% respectively.

    So:

    0.01×0.541

    0.01×0.541 + 0.99×0.942

    or

    0.00541

    0.00541 + 0.93258

    or

    0.00541

    0.93799

    or

    0.0057

    or

    0.57%!

    If a woman receives a positive mammography result for breast cancer the probability she actually suffers from the disease is only 0.57%

    Reference

    https://pubs.rsna.org/doi/abs/10.1148/radiol.2019182394

  • Widespread diagnostic mistakes during periodic preventive screening mammographies, that lead to unnecessary mastectomies and irradiations to hundreds of thousands of healthy women!

    References

    http://sites.jamanetwork.com/breastcancerscreening/images/Infographic-Helping-and-Harming-Women-Through-Screening.pdf
    https://www.ncbi.nlm.nih.gov/pubmed/24380095
    http://jamanetwork.com/journals/jamainternalmedicine/article-abstract/1792915
    http://www.nejm.org/doi/pdf/10.1056/NEJM199804163381601
    http://annals.org/aim/article/474984/cumulative-probability-false-positive-recall-biopsy-recommendation-after-10-years
    http://annals.org/aim/article/2480754/harms-breast-cancer-screening-systematic-review-update-2009-u-s
    https://www.youtube.com/watch?v=H3NlFALac2A
    https://www.youtube.com/watch?v=JxDnRMU-l7w
    https://www.youtube.com/watch?v=e3cG1xToqic
    https://www.youtube.com/watch?v=IwoIBTJD1VQ
    https://www.youtube.com/watch?v=D2k8DAjM4Gg
    https://www.youtube.com/watch?v=8A9xuLmUHcQ

  • Why did you decide to get a mammogram?

    The world’s leader in breast mammography Dr. Laszlo Tabar Answers: What Is the Value of Routine Screening & Mammography? 

    ‪#‎BreastCancer‬ ‪#‎Mammogram‬ #BreastCancerScreening