The Bond Between Sleep and Cancer Of The Prostate

 

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Researchers found that men younger than 65 who slept just three to five hours a night were 55 percent more likely to develop fatal prostate cancer than those who got the recommended seven hours of shuteye nightly. And, six hours of sleep a night was linked to a 29 percent higher risk of prostate cancer death compared to seven hours. The association between sleep duration and prostate cancer (PCa) risk is still unclear. We performed a systematic review and meta-analysis to explore if sleep duration is associated with PCa in men.

A comprehensive literature search was conducted in November 2019 based on the Pubmed, Embase, and Cochrane databases. And while the link between prostate cancer and nocturnal annoyances “remains unclear”, Dr Chung suspects it might be an issue with the hormone melatonin which regulates sleep-wake cycles and. Six hours of sleep a night was linked to a 29 percent higher risk of prostate cancer death compared to the recommended seven hours.

“ the findings contribute to evidence that the body’s natural sleep/wake cycle — circadian rhythms — might play a role in prostate cancer development”. “Lack of sleep may also contribute to the disruption of genes involved in tumor suppression”. There are some data to suggest that insufficient sleep, including short sleep duration and sleep disruption, may be associated with an increased risk of cancer. We investigated the association between sleep duration and sleep disruption and risk of prostate cancer.

Over the years, there’s been growing evidence of a link between ejaculation and lower chances of prostate cancer. But the 2016 results of a major study made the strongest case yet. Men with higher levels of the sleep hormone melatonin may be less likely to develop prostate cancer, a new study suggests. The research also revealed that men who had higher levels of melatonin in.

Disruptions in the body’s “biological clock,” which controls sleep and thousands of other functions, may raise the odds of cancers of the breast, colon, ovaries and prostate. Exposure to light while working overnight shifts for several years may reduce levels of melatonin, encouraging cancer to grow. In recent years, research has challenged the link between testosterone and prostate cancer.

Some studies have contradicted it, finding a higher risk of prostate cancer among men with low.

List of related literature:

It interferes with a peaceful sleep, and can be conducive to cancers of the prostate, bladder, and the pancreas.

“Chinese Health Care Secrets: A Natural Lifestyle Approach” by Henry B. Lin
from Chinese Health Care Secrets: A Natural Lifestyle Approach
by Henry B. Lin
Llewellyn Publications, 2000

In men, sleep disturbances may be caused by frequent urination at night associated with prostate enlargement or HT for prostate cancer.

“Lewis's Medical-Surgical Nursing: Assessment and Management of Clinical Problems” by Diane Brown, Helen Edwards, Lesley Seaton, Thomas Buckley
from Lewis’s Medical-Surgical Nursing: Assessment and Management of Clinical Problems
by Diane Brown, Helen Edwards, et. al.
Elsevier Health Sciences, 2017

Unlike nonmalignant causes of back pain, the back pain of metastatic prostate cancer is usually worse at night.

“The Washington Manual of Oncology” by Ramaswamy Govindan, Washington University (Saint Louis, Mo.). School of Medicine
from The Washington Manual of Oncology
by Ramaswamy Govindan, Washington University (Saint Louis, Mo.). School of Medicine
Wolters Kluwer Health/Lippincott Williams & Wilkins, 2008

They also assessed sleep at different phases of the cancer trajectory and in patients receiving various treatment regimens, making comparisons across studies virtually impossible.

“Supportive Oncology E-Book” by Mellar P. Davis, Petra Feyer, Petra Ortner, Camilla Zimmermann
from Supportive Oncology E-Book
by Mellar P. Davis, Petra Feyer, et. al.
Elsevier Health Sciences, 2011

In studies by Meikle and Stanish (1982), brothers of cases had four times higher cumulative rates of prostate cancer than brothers-in-law or males of the general population, thereby reflecting existence of genetic factors that increase the risk of neoplastic development in the prostate gland.

“Epidemiology of Chronic Disease: Global Perspectives” by Randall E. Harris
from Epidemiology of Chronic Disease: Global Perspectives
by Randall E. Harris
Jones & Bartlett Learning, 2013

In general, it appears that there are different aspects of prostate cancer and its treatment that are more stressful for you and your spouse or partner.

“100 Questions & Answers About Prostate Cancer” by Pamela Ellsworth
from 100 Questions & Answers About Prostate Cancer
by Pamela Ellsworth
Jones & Bartlett Learning, 2009

The prostate cancer findings raise hopes for discovering similar phenomena in other

“Journal of the National Cancer Institute: JNCI.” by National Cancer Institute (U.S.), National Institutes of Health (U.S.)
from Journal of the National Cancer Institute: JNCI.
by National Cancer Institute (U.S.), National Institutes of Health (U.S.)
U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, 2010

In patients with hormone-refractory prostate cancer, bony involvement can be found in 85% of patients, soft tissue or nodal involvement in 25%, and visceral metastases (mainly to lung and liver) in 18%.

“Netter Collection of Medical Illustrations: Reproductive System E-Book” by Roger P. Smith, Paul Turek
from Netter Collection of Medical Illustrations: Reproductive System E-Book
by Roger P. Smith, Paul Turek
Elsevier Health Sciences, 2011

It is also common for both BPH and prostate cancer to occur simultaneously.

“The Nurse Practitioner in Urology” by Michelle Lajiness, Susanne Quallich
from The Nurse Practitioner in Urology
by Michelle Lajiness, Susanne Quallich
Springer International Publishing, 2016

In addition, the site of metastases confers a prognostic impact in patients with prostate cancer.

“Management of Advanced Prostate Cancer” by Choung Soo Kim
from Management of Advanced Prostate Cancer
by Choung Soo Kim
Springer Singapore, 2018

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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11 comments

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