Staying away from Pseudomedicine for Alzheimer’s and Brain Health

 

Science and Pseudoscience Podcast Episode 1 Zach Bush

Video taken from the channel: Mad in America


 

What Foods Fight Dementia?

Video taken from the channel: WS Westwood


 

Preventing Alzheimer’s disease with FOOD

Video taken from the channel: Max Lugavere


 

The MIND Diet for Brain Health with Leslie Beck

Video taken from the channel: Medcan


 

“Non-Evidence Based Treatments for Dementia & Brain Health” by Joanna Hellmuth, MD, MHS

Video taken from the channel: UCSF Memory and Aging Center


 

How to Avoid Alzheimer’s and Build a Better Brain (Webinar Replay)

Video taken from the channel: Forks Over Knives


 

Brain Health Promotion Strategies: Separating Reality-Based Hope From Hopeless Pseudo-Medicine

Video taken from the channel: University of California Television (UCTV)


Learn more about women and brain health. A piece in the recent issue of JAMA highlights the increase in “pseudomedicine” for dementia and brain health. Pseudomedicine refers to “interventions that are promoted as scientifically-supported treatments but lack credible efficacy data.” In short, these treatments aren’t proven to help cognitive health. This fake news of health information, the authors wrote, is helping to drive a huge market — $3.2 billion in over-the-counter “treatments” to improve cognition and brain health in 2016 — that gives false hope to sufferers of dementia.

Pseudomedicine is especially problematic among older patients and family members concerned about memory loss and desperate for effective therapies to slow or stop the progression of Alzheimer’s disease. Other examples of pseudomedicine include recommendations for brain healthy diet plans. The US population is aging, and with it is an increasing prevalence of Alzheimer disease, which lacks effective approaches for prevention or a cure. 1 Many individuals are concerned about developing cognitive changes and dementia.

With increasing amounts of readily accessible information, people independently seek and find material about brain health. As fears about Alzheimer’s and other forms of dementia are exploding, willingness to buy the pitch that brain health can come in a pill is rising as well. But scientists are calling foul, saying. “For the other 99%, amyloid and tau are closely associated with Alzheimer’s, but many things may contribute to the development of symptoms, such as inflammation in the brain, vascular risk factors, and lifestyle.” Improve your lifestyle for Alzheimer’s prevention. Healthy habits may help ward off Alzheimer’s.

Brain health – learn about lifestyle habits that can help keep your body and brain healthy, while potentially reducing your risk of cognitive decline. Get information and resources for Alzheimer’s and other dementias from the Alzheimer’s. Population-based studies suggest that factors associated with overall good health may also reduce the risk of dementia and cognitive decline.

These factors include regular physical activity, eating a healthy diet and keeping your brain. At least three servings of whole grains a day Green leafy vegetables (such as salad) at least six times a week Other vegetables at least once a day Berries at least twice a week Red meat less than four times a week Fish. A recent article has highlighted a steep rise in “pseudomedicine” that markets many dietary supplements as benefiting brain health or preventing dementia.

Because there are currently no approved drugs to prevent or cure dementia.

List of related literature:

Adult clients could be incentivized to improve their diet by new research findings about the MediterraneanDash Intervention for Neurodegenerative Delay (MIND) diet shown to reduce the risk for Alzheimer’s disease by 53% in rigorous adherents (35% in moderate adherents) (Di Fiore, 2015).

“Conceptual Foundations E-Book: The Bridge to Professional Nursing Practice” by Elizabeth E. Friberg
from Conceptual Foundations E-Book: The Bridge to Professional Nursing Practice
by Elizabeth E. Friberg
Elsevier Health Sciences, 2019

There is some epidemiological evidence that oestrogens and statins (HMGCoA reductase inhibitors) may also reduce the risk of developing Alzheimer’s disease and other dementias.

“Clinical Pharmacy (2nd Edition)” by NA Hughes, Jeffery D. Hughes
from Clinical Pharmacy (2nd Edition)
by NA Hughes, Jeffery D. Hughes
Macmillan Education UK, 2001

Based on scientific evidence, the authors suggested that crocins could be a promising agent for the prevention or treatment of Alzheimer’s disease.

“Saffron: Science, Technology and Health” by Alireza Koocheki, Mohammad Khajeh-Hosseini
from Saffron: Science, Technology and Health
by Alireza Koocheki, Mohammad Khajeh-Hosseini
Elsevier Science & Technology, 2019

Crocus sativus may inhibit the aggregation and deposition of amyloid β in the human brain and may therefore be useful in Alzheimer’s disease.

“Edible Medicinal and Non Medicinal Plants: Volume 8, Flowers” by T. K. Lim
from Edible Medicinal and Non Medicinal Plants: Volume 8, Flowers
by T. K. Lim
Springer Netherlands, 2014

Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer’s disease (GuidAge): a randomised placebo-controlled trial.

“Handbook on the Neuropsychology of Aging and Dementia” by Lisa D. Ravdin, Heather L. Katzen
from Handbook on the Neuropsychology of Aging and Dementia
by Lisa D. Ravdin, Heather L. Katzen
Springer International Publishing, 2019

In addition, it has been reported that nutritional substances or food stuffs such as fish, vitamin, and a moderate amount of alcohol decrease the risk for dementia and Alzheimer’s disease (AD) (Kalmijn et al. 1997, 2004; Luchsinger and Mayeux 2004).

“Handbook of Behavior, Food and Nutrition” by Victor R. Preedy, Ronald Ross Watson, Colin R. Martin
from Handbook of Behavior, Food and Nutrition
by Victor R. Preedy, Ronald Ross Watson, Colin R. Martin
Springer New York, 2011

To learn more, patients can be advised to talk with their doctor or to visit the Alzheimer’s Disease Education and Referral (ADEAR) Center’s listing of clinical trials on the National Institute on Aging Web site (www.nia.nih.gov/Alzheimers/ ResearchInformation/ClinicalTrials).

“Dental Management of the Medically Compromised Patient E-Book” by James W. Little, Donald Falace, Craig Miller, Nelson L. Rhodus
from Dental Management of the Medically Compromised Patient E-Book
by James W. Little, Donald Falace, et. al.
Elsevier Health Sciences, 2012

Stereotactic radiosurgery for brain metastases: a case-matched study comparing treatment results for patients 80 years of age or older versus patients 65-79 years of age.

“Abeloff's Clinical Oncology E-Book” by John E. Niederhuber, James O. Armitage, James H Doroshow, Michael B. Kastan, Joel E. Tepper
from Abeloff’s Clinical Oncology E-Book
by John E. Niederhuber, James O. Armitage, et. al.
Elsevier Health Sciences, 2019

A comment by Minervaló in BMJ on a report in JAMA concluded that the treatment with ERT prevents the risk of developing Alzheimer’s and reduces the risk by 30%.

“Textbook of Oral and Maxillofacial Surgery” by Balaji
from Textbook of Oral and Maxillofacial Surgery
by Balaji
Elsevier (A Divisionof Reed Elsevier India Pvt. Limited), 2009

National Institute on Aging-Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach.

“Neuropathology E-Book: A Reference Text of CNS Pathology” by David Ellison, Seth Love, Leila Maria Cardao Chimelli, Brian Harding, James S. Lowe, Harry V. Vinters, Sebastian Brandner, William H Yong
from Neuropathology E-Book: A Reference Text of CNS Pathology
by David Ellison, Seth Love, et. al.
Elsevier Health Sciences, 2012

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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23 comments

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  • Max Lugavere I have have mind psych drugs they have aluminium in drug & it’s related to the onslaught of mind fog to alzheimer’s I have read many books on my research to aging longevity and no chemical in in diet and ingredients that clear though pattern I read you book & pass this book on to others many at that point

  • I am plant based, actually have the forks over knives recipe service, but still have problems with high triglycerides, even with exercise. Is there anything else I can do to control this without medication?

  • I’ll help pass this video on by linking it. With some of the garbage that tends on YT this webinar should have millions of views. Their book is incredibly valuable. ������

  • Dr. Greger @ Nutrition Facts has sited many studies that link high fat, meat based diets to dementia and Alzheimer’s. It’s fairly clear that artery constriction and inflammation play a major role in these two diseases. Both are caused by the ordinary American diet. It’s not a mystery. We should educate people with the facts.

  • Dr. Wallach Talks about Eggs & Alzheimers
    https://youtu.be/CX9wExhcdRg
    Dr. Joel Wallach on WHY 90 In 2 MINUTES!
    https://youtu.be/xPqt9-V3R9Y

  • Thanks to the three of you for an excellent webinar. I didn’t get to watch it live, due to participating in the Midwest vegetable harvest. In my neck of the woods, a severe harvest labor shortage is somewhat mitigated by retirees who are willing to help.

    I’ve been plant based for about 18 months, after stumbling across “The China Study.” Since then, I have used voracious WFPB information consumption as a way of maintaining sanity in a culture that has insane eating habits.

    My mother-in-law is suffering from cognitive impairment and it has increased dramatically this year, so the timing of this webinar was excellent.

  • I watched this with interest. There are a lot people out there selling snake oil. I wish there were more meat to the criticism of Bredesen.

    Has Dr. Hellmuth read Bredesen’s book? He actually tried to get an IRB approved clinical trial with four different test groups, but they rejected it because the study was allegedly testing too many variables. But if Bredesen’s argument that APP is a dependence receptor, and the way it is cut is contingent on a number of factors, then you’re not going to solve Alzheimer’s if you focus on monotherapies. Unfortunately, the IRB folks are not likely to approve clinical trials if you take a multi-causational approach.

    Also, Dr. Hellmuth seems to insinuate that “The End of Alzheimer’s” book is a conflict of interest because Bredesen got a study published after the publication of the book. Are you not allowed to publish research after you publish a book?

    Dr. Hellmuth doesn’t engage with the actual scientific merit of Bredesen’s research. The End of Alzheimer’s is not just based on the case studies she mentions, but his other research published in places like the Annals of Neurology and Cell Death Differ.

    I’d actually love to read/listen to critical engagement with Bredesen’s scientific arguments.

  • So, give us the data…
    1 How many meat eaters get Alzheimer’s?
    2 How many vegetarians get Alzheimer’s?
    I have heard these extreme claims by vegetarians for years now on YouTube and elsewhere about how you can improve your health, get rid of diabetes, high blood pressure, dementia and all kinds of chronic diseases after only one month of eating vegetarian. Well, I tried it, and I admit I feel better, but I honestly do not like the food as much it is not as satisfying, but none of my vital measurements really changed. The vegan supporters are just as dishonest, but probably more correct than not, than the carnivore supporters, but both sides are lying.

  • I heard a guy reversed his mums late stage condition using dark chocolate, walnuts & coconut oil apparently shes completely normal again now!

  • Leslie; great session. Loved the quiz and am keeping a spreadsheet of what I eat to see how (really) close to meeting the guidelines mind-diet-tracker. Have been talking about this diet for several years when I give a talk on dementia. Stay well, Karen Henderson LTC Planning Network.

  • Stay happier, healthier longer: become a vampire and drink the blood of virgins, but they are becoming harder to find. Dr. Joanna Hellmuth, please stop making your voice go up that high a pitch, it’s very distracting, and makes my dog’s ears itch.

  • Actually getting dementia and Alzheimer’s is hereditary. My mother ate exactly like this but she got it anyway. This guy doesn’t know what he’s talking about

  • 40:55 It is curious. I wonder if there is a size to the number of functions of a given gene, that maybe there may be many kinds of small ones which do not provide as much function as one slightly larger?

  • 1, from Nampa, Idaho….near Boise. My mom was diagnosed via drug trial testing with Alzheimers in 2017, was part of the Daybreak study by AstraZeneca and Eli Lilly. The three year study was abandoned a month after my mom quit due to horrible side effects one year into it and we started dealing with lifestyle issues. Eliminating Benadryl as a sleep aid and replacing it with essential oils, exercise, moving towards a whole food plant based diet, attended the March 2019 conference on women, heart disease and Alzheimers, met Drs. Dean and Ayesha Sherzai there. My mom has experienced a rather dramatic reversal in her disease and made gains in her window of backward and forward awareness and memory. She has also augmented her treatment with HBOT treatments in January and again this fall, brain mapping and bio-feedback therapies. She is a vastly different person than she was 2 years ago, due to NEURO protocol and attentiveness to lifestyle issues, even at age 82. Such a story of hope.

  • Dr Zach Bush MD ought to win the Nobel Prize for Medicine. There probably has not been one discovery more globally impactful in health than the disruption of communication in our microbiome and that being the causation of modern day diseases and maladies. Restore along with regeneration of our soil are more important than anything else in the survival of our species.

  • Ahhh, this micro-biome topic is not at all new information. Actually, nothing that he mentions is all that new. Nonetheless, this is a great podcast. Needs more views! Maybe people will have a light bulb moment?

    He talks like a research geek that has connected the dots. Needs more views.

    This podcast really could go on for hours. It just glanced the surface.

  • I am a 71 year old female, I was diagnosed of Amyotrophic lateral sclerosis (ALS) in 2015, my symptoms started out with muscle weakness, difficulty speaking, fatigue, double vision, difficulty swallowing and anxiety. I was unable to go back to work, I tried Riluzole (Rilutek) for about a year. Tried every shot available, but nothing worked.My ALS Disease got significantly worse and unbearable because of my cognitive thinking. In 2017, I started on ALS Herbal formula from Natural Herbal Gardens, the treatment worked incredibly for my ALS condition. I used the Natural ALS Herbal formula for a total time period of 3 months, it totally reversed my ALS. I had a total decline of all symptoms including muscle spasms, difficulty swallowing, drooling and others. Sometimes, i totally forget i ever had ALS. Visit Natural Herbal Gardens web-site ww w. naturalherbalgardens. com. I am very pleased with this treatment. I eat well, sleep well and exercise regularly. My attitude is extremely positive.

  • Great, great interview. Direct and actionable information. Keep doing what you’re doing and keep digging man, new studies are always cropping up to integrate into the overall picture #GeniusFoods2

  • Rallis Olive Oil at the Total Health Show
    https://youtu.be/ZmR6RjO59EA
    Udo’s Oil 3-6-9 Blend with Udo Erasmus
    https://youtu.be/2aqmcTDo550

  • Dr. Zach Bush has come to bring truths to humanity, to serve our awakening! He is a master alchemist and because of his path into our linearly programmed western medicine, many will hear what is life-critical if we are to survive as a species. I just returned from putting the world’s leading endocrinologists, scientists, and whistle-blowers on camera where Zach was standing by to connect-the-dots to other scientists, so we can come together to empower this information virally. WE MUST ERADICATE GLYPHOSATE FROM OUR PLANET. GO ORGANIC TO HEAL/RESTORE YOUR LIFE!

  • Thank you for this much needed information!! My father had Alzheimer’s I’m a t1d,so started WFPB,no sugar,oil,salt added and low fat 2 years ago….wish this info was brought to my attention sooner!!❤ Children MUST get this information from day 1!!!❤

  • Those are great points about preserving hope. Maybe doctors shouldn’t be the ones to have those difficult conversations. Maybe there should be other professionals with a different type of training to have those conversations and follow up with the patient. That’s a lot of responsibility to put on doctors. It’s like asking doctors to be therapists or spiritual care providers when doctors have no training in this area.

  • One in three men is not infertile. https://www.hhs.gov/opa/reproductive-health/fact-sheets/male-infertility/index.html Autism is being diagnosed more. https://bigthink.com/neurobonkers/no-half-of-all-children-wont-be-autistic-by-2025-whatever-facebook-tells-you
    I stopped listening after that point. It’s disappointing to see this channel circulate a fearmongering quack. Science and pseudoscience, indeed.