CME: Secondary Cancers Occurring After Cancer Treatment: Prevention of Breast Cancer
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The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. Also, 20 percent of the women had an inherited gene mutation that increases the risk of breast cancer, according to the study published Dec. 7 in the journal Cancer. MONDAY, Dec. 7, 2015 (HealthDay News) Researchers say they’re zeroing in on factors that may increase the risk of leukemia after breast cancer treatment.
The findings are. Researchers Focus on Risk Factors for Leukemia After Breast Cancer Treatment. Family history of cancer, inherited gene mutation seem to raise chances of secondary malignancy. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukemia later, the researchers said.
The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukaemia later, the researchers said. Read: Gene Mutation.
The excess risk (the excess number of cases of leukemia per 10,000 patients) within the first 10 years after the diagnosis of breast cancer was estimated by multiplying the relative risk minus. While the risk of developing leukemia after radiation therapy or chemotherapy to treat early-stage breast cancer is VERY small, a large study suggests that this risk is twice as high as has been reported. The research. Specific risk factors for leukemia include: Exposure to cancer-causing agents. People exposed to high doses of radiation (from the explosion of an atomic bomb, working in an atomic weapons plant, or a nuclear reactor accident.
Radiation treatment for cancer has also been linked to an increased risk of AML. The risk varies based on the amount of radiation given and what area is treated. The possible risks of leukemia from exposure.
There is a small increased risk of developing leukemia and myelodysplastic syndrome after receiving certain chemotherapy (chemo) drugs for early breast cancer. The risk is higher if both chemo and radiation therapy.
List of related literature:
|from Holland-Frei Cancer Medicine 8|
|from The Chemotherapy Source Book|
|from Abeloff’s Clinical Oncology E-Book|
|from Biomarkers in Toxicology|
|from A Guide to Evidence-based Integrative and Complementary Medicine|
|from Goddesses Never Age: The Secret Prescription for Radiance, Vitality, and Well-Being|
|from Williams Textbook of Endocrinology|
|from Diseases and Disorders|
|from Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines|
|from Cancer Nursing: Principles and Practice|