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TUESDAY, Oct. 22 (HealthDay News) A diagnosis of pancreatic cancer usually carries with it a poor prognosis, and the news may be even worse for those who are obese: It could mean dying two to. TUESDAY, Oct.
22, 2013 (HealthDay News) A diagnosis of pancreatic cancer usually carries with it a poor prognosis, and the news may be even worse for those who are obese: It could mean dying two to three months sooner than pancreatic cancer patients of normal weight, new research shows. TUESDAY, Oct. 22 (HealthDay News) A diagnosis of pancreatic cancer usually carries with it a poor prognosis, and the news may be even worse for those who are obese: It could mean dying two to three months sooner than pancreatic cancer patients of normal weight, new research shows.
Prior studies have tied obesity to a higher chance of getting pancreatic cancer, but the new study. Colon cancer rates and pancreatic cancer deaths rose by 10% worldwide between 1990 and 2017, according to a new study of global trends in digestive diseases. In pancreatic cancer, increased BMI has been reported to be an adverse prognostic factor for survival after surgery in two surgical series of 285 and 356 patients, respectively.16, 17However, another surgical report of 306 patients undergoing resection of pancreatic adenocarcinoma reported increased postoperative complications in obese patients, but the slight decrease in survival. Further, other studies found no relationship between obesity and the long-term survival of patients with PC [ 31, 32 ]. Large prospective studies of cohorts found that BMI ≥35 kg/m 2 is associated with significantly shorter survival of patients with PC [ 33 ], which is confirmed by a multicenter cohort study [ 34] and a meta-analysis [ 35 ].
Pancreatic cancer is currently the fourth leading cause of cancer death but is projected to be the second leading cause before 2020 (Pancreatic Cancer Action Network, 2012).In 2013, 45 220 Americans will be diagnosed with pancreatic cancer and 85% (38 460) of them will die from the disease (Siegel et al, 2013).Thus, identifying factors that impact pancreatic cancer survival. In the series of 313 patients diagnosed with pancreatic cancer, 98 (31.3%) were initially misdiagnosed, with a total of 119 diagnoses other than pancreatic cancer, he said. The most common misdiagnosis was gallbladder disease, which led to a cholecystectomy in 38 cases, followed by gastroesophageal reflux disease in 15 cases, and peptic ulcer. We have also conducted a meta-analysis of 29 studies on diabetes and overall survival of patients with pancreatic cancer and found a reduced survival of patients with diabetes in 25 clinic-based studies (pooled HR, 1.13; 95% CI, 1.02 to 1.25), but not in four cohort studies 4–7 (pooled HR, 1.12; 95% CI, 0.95 to 1.32).
The prevalence of. “Before our work, the largest study looking at long-term survivors of pancreatic cancer had only eight patients,” Dr. Balachandran says. “We had 82.” To further define what makes a good neoantigen, the MSK team joined up with computational biologists Benjamin Greenbaum and Marta Luksza from the Icahn School of Medicine at Mount Sinai.
List of related literature:
|from Handbook of Anthropometry: Physical Measures of Human Form in Health and Disease|
|from Nutritional Oncology|
|from Conn’s Current Therapy 2019|
|from Conn’s Current Therapy 2020, E-Book|
|from The Biology of Cancer|
|from Cancer Nursing: Principles and Practice|
|from Holland-Frei Cancer Medicine 8|
|from Krause’s Food & the Nutrition Care Process E-Book|
|from Holland-Frei Cancer Medicine Cloth|
|from Diseases and Disorders|