New Moms’ Codeine Use Lower Since Health Warnings

 

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TUESDAY, May 12, 2015 (HealthDay News) Fewer new mothers have been prescribed the painkiller codeine since public health officials warned about a rare, but potential risk of overdose for breast-feeding babies, a new study says. By Amy Norton. HealthDay Reporter.

TUESDAY, May 12, 2015 (HealthDay News) Fewer new mothers have been prescribed the painkiller codeine since public health officials warned about a rare, but potential risk of overdose for breast-feeding babies, a new study says. Experts said the study results, reported in the May 12 Journal of the American Medical. New Moms’ Codeine Use Down Since Health Warnings. In rare cases, a woman metabolizes the drug faster, getting too much into breast-milk. Please note: This article was published more than one year ago.

The facts and conclusions presented may have since changed and may no longer be accurate. And “More information” links may no longer work. April 21, 2017 There are new warnings from the U.S.

Food and Drug Administration (FDA) about the use of codeine and tramadol in children and nursing mothers. The message about codeine and tramadol is specific: Don’t give it to children under 12. For children 12-18 and breast-feeding mothers, these medications should be limited.

Codeine is among the most common drugs taken by new mothers, FDA officials said. It is included in several prescription pain drugs and in some over-the-counter cough syrups. According to Health. Safety review update of codeine use in children; new Boxed Warning and Contraindication on use after tonsillectomy and/or adenoidectomy. This update is in follow-up to the. FDA Drug Safety.

Aug. 18, 2007 The FDA today warned breastfeeding mothers who take codeine for after-birth pain to carefully watch their babies for signs of life-threatening drug side effects. FDA statement from Douglas Throckmorton, M.D., Deputy Center Director for Regulatory Programs, Center for Drug Evaluation and Research, on new warnings about the use of codeine and tramadol in. Codeine is not for use in anyone under 18 years old.

Taking codeine during pregnancy may cause life-threatening withdrawal symptoms in the newborn. Fatal side effects can occur if you use codeine with alcohol, or with other drugs that cause drowsiness or slow your breathing. Before taking this medicine. Neonatal Opioid Withdrawal Syndrome.

Prolonged use of codeine sulfate during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts.

List of related literature:

The FDA advisory recommends that if codeine is prescribed for a breastfeeding woman, the lowest dose possible be used, and the woman should be counseled to watch for signs of excessive sleepiness and/or difficulty nursing or rousing the infant.

“Pharmacology for Women's Health” by King, Tekoa L. King, Mary C. Brucker
from Pharmacology for Women’s Health
by King, Tekoa L. King, Mary C. Brucker
Jones & Bartlett Learning, 2010

In addition, codeine should not be given to patients who are known ultrarapid metabolizers of codeine, including mothers who are breastfeeding, as breast-fed infants have died when exposed to high levels of morphine (codeine converts to morphine) in breast milk.

“2020 Nurse's Drug Handbook” by Jones & Bartlett Learning
from 2020 Nurse’s Drug Handbook
by Jones & Bartlett Learning
Jones & Bartlett Learning, 2019

Because no toxicity was observed in the neonates, the authors concluded that short-term use of codeine (up to four 60-mg doses) was safe for healthy, full-term infants in the first days of life (16).

“Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk” by Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe
from Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk
by Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe
Wolters Kluwer Health/Lippincott Williams & Wilkins, 2011

The authors suggested that moderate codeine use during breast-feeding (no more than four doses of 60 mg) is probably safe, and this has been subsequently taken to be so (26).

“Meyler's Side Effects of Analgesics and Anti-inflammatory Drugs” by Jeffrey K. Aronson
from Meyler’s Side Effects of Analgesics and Anti-inflammatory Drugs
by Jeffrey K. Aronson
Elsevier Science, 2009

A U.S. Food and Drug Administration (FDA) warning in 2007 noted that a published case report of an infant death raised concern that breast-fed babies may be at increased risk of morphine overdose if their mothers are taking codeine and are ultrarapid metabolizers of the drug.

“Pharmacology E-Book: with STUDENT CONSULT Online Access” by George M. Brenner, Craig W. Stevens
from Pharmacology E-Book: with STUDENT CONSULT Online Access
by George M. Brenner, Craig W. Stevens
Elsevier Health Sciences, 2012

This important study emphasises the safety of breastfeeding in mothers requiring medicines, although a note of caution is required regarding over-the-counter codeine-containing analgesia.

“Rennie & Roberton's Textbook of Neonatology E-Book” by Janet M. Rennie
from Rennie & Roberton’s Textbook of Neonatology E-Book
by Janet M. Rennie
Elsevier Health Sciences, 2012

The safe use of codeine during breastfeeding is dependent on knowing how the mother handles the drug.

“Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment” by Christof Schaefer, Paul W.J. Peters, Richard K Miller
from Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment
by Christof Schaefer, Paul W.J. Peters, Richard K Miller
Elsevier Science, 2014

On 17 August 2007, the FDA warned breastfeeding mothers who take codeine, either in combination with another analgesic or in any form of cough syrup, that babies are at increased risk for morphine overdose.

“The Dentist's Drug and Prescription Guide” by Mea A. Weinberg, Stuart J. Froum, Stuart L. Segelnick
from The Dentist’s Drug and Prescription Guide
by Mea A. Weinberg, Stuart J. Froum, Stuart L. Segelnick
Wiley, 2020

The updated warning notes that breast-feeding is not recommended when taking codeine because of the risk for serious adverse reactions.170 In addition, genetic variability in UGT2B7 may increase the formation of active morphine-6-glucuronide.

“Chestnut's Obstetric Anesthesia E-Book” by David H. Chestnut, Cynthia A Wong, Lawrence C Tsen, Warwick D Ngan Kee, Yaakov Beilin, Jill Mhyre, Brian T. Bateman, Naveen Nathan
from Chestnut’s Obstetric Anesthesia E-Book
by David H. Chestnut, Cynthia A Wong, et. al.
Elsevier Health Sciences, 2019

Although short-term use of codeine by a breastfeeding mother appears to be harmless, there is one case where the mother was taking codeine and acetaminophen for episiotomy pain and breastfeeding.

“Obstetrics: Normal and Problem Pregnancies E-Book” by Mark B Landon, Henry L Galan, Eric R. M. Jauniaux, Deborah A Driscoll, Vincenzo Berghella, William A Grobman, Sarah J Kilpatrick, Alison G Cahill
from Obstetrics: Normal and Problem Pregnancies E-Book
by Mark B Landon, Henry L Galan, et. al.
Elsevier Health Sciences, 2020

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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22 comments

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  • This is what happens when you start listening to American Rap music. Stupid mu mu people. So they have money for codeine?��

    They are bored and stupid. There’s bigger issues like not educating their women and government corruption as well as child abuse that it continually ignored.

  • You need to look at the book The Lies My Dr Told me by Dr Ken Berry. My case was exactly that. When diagnosed with type 2 diabeties I was told there was no cure and I would need to be on meds the rest of my life. Determined there must be another way I did my own research. To my surprise there was a massive amount of high grade research showing change of lifestyle in particular food choices was all I needed to do. It worked in a matter of weeks I had a retest and my A1C was back below 5. I was no longer diabetic. Look at the work of Dr Michael Mosley his book the Fast 800

  • There is a hospital Dr in the UK who tries to treat people without drugs or less drugs. He has a YouTube channel too. I forgot it. I think they are twin Drs. I hope you are better now.

  • Thanks for sharing your experience Lee. Sad that the system is the way it is and you had to go through this. Glad you also made your disclaimer at the start that this is just your experience and not an indictment on medicine as whole.

    Seeing a lot of dangerous comments here though regarding pharmaceutical drugs in general. I’m glad people remain skeptical of the health system and the overprescription of addictive pain meds, but I hope it doesn’t extend to the entire concept of pharmaceutical drugs and ‘western medicine’. Pain meds are just part of that there’s so many other types of medicine that are doing great things.
    A lot of doctors (who are humans, not part of some grand conspiracy) have saved so many lives over the years and a lot of times they are still our best bet. God knows I wouldn’t have a father anymore if not for them.
    Instead of demonizing the healthcare frontliners like doctors and nurses (who are under a lot of pressure from the demands of the flawed system). We should go after the real problem the system itself. The system is really showing its cracks and needs to be managed and funded better, instead of the insistence of cutting funds from it.

    I’m glad that Lee is taking this approach of looking at the overarching problem instead of just focusing on the frontliners. More power to you. Stay strong.

  • Hi
    For sure I would need closer examination of your issue but I think the Bowen Technique therapy is worth to try.
    If you live close enough to Edinburgh I could do it for you. Do not worry about cost.
    If you are interested please contact me.
    All the best.

  • She wasn’t being that honest with you, she wants you to be on more drugs, that have more side effects so they can give you more drugs to combat the side effects, because that’s how big Phama works. Big Phama and the food industry work together, biggest money making industries in the world. Have you researched Alkaline diet! Dr Sebi was arrested and murdered while incarcerated. They are slowly killing you, while you make them money

  • Man this is awful, hope you can get through this. If really nothing work within the NHS maybe the only way is try to get treated privately even if it’s expensive, and pay off the debt slowly. It’s sad but if it can save your life and be healthy it may be a way out…

  • Tories don’t care about NHS because it was the Labour party who introduced it.The best thing that ever happened to this country.Hope your keeping well.

  • NHS is crap! They told my sister she had a migraine when it was actually a brain hemorrhage, and they sent her home to die, they told my dad he had chronic asthma when he had lung cancer and they damaged the nerves in my spine by administering an epidural in a slap happy that’ll do way. During this so-called pandemic while sheeple are out clapping them, the NHS are not looking after cancer patients and many others and hospitals are practically empty.

  • Are you ok? The nhs got a huge fund from captain Tom just wondering if they are giving you the right medicine, is it all going to corona virus?

  • As someone who suffers sever chronic pain, I am on three 5 mg pain pils a day. I was put on Methadone at one point and it was one of the most horrific experiences in my life. I hav 2 rare painful medical conditions and 13 other medical diagnosis. Without the ability to control pain, you have no quality of life. I would be in a wheelchair. The Patches are cruel and make you a zombie, and it sees off my Cyclic vomiting syndrome. When doctors prescribe tons of other meds, it poisons the system. The docs get money for prescribing massive amounts of money from big Pharm. It needs to be stopped so Chronically ill can get proper medical care without being treated like a “Drug Seeker”.

  • Please contact a good professional Medical Herbalist, pm me and I will give you the contact of my friend who has your outlook and is also a gardener and would be great to talk with

  • Hi I came across our video looking at all the medication and I truly understand where you coming from, I myself suffer from chronic lower back pain and been through all or even more opioids now for 10 years.and still taking them you can not function at all.

  • God bless you! I am so unbelievably sooo for what you’re going through. You are such a beautiful soul, and deserve so much better! I only pray things get better for all the helpless out there

  • In the western world it’s the same. Do not take drugs that the doctors give you. Just because they are doctors does not mean they know what’s best for you.
    Nutrition. Herbs. Go the natural route. Look up Dr. Berg.

  • I was thinking you most probably already have but have you tried a whole food plant based diet? Check out Dr. Neal Barnard’s videos on You Tube and that will inevitably lead you to a host of others devoted to WFPB benefits in terms of health.

  • I’ve grown up seeing my mum being put on the waiting list and every time she was due an appointment something had gone wrong and no one ever took responsibility. GPs put minimum effort in finding out what the problems where and they instead put her on meds just like you said…disgusting! So many ppl in the NHS are pouring their souls and hearts into their jobs, no one sees that because of those who don’t, mess up & make it hard! Stay strong we love you man!

  • dude, drop all that shit, reduce oxy very slowly, take turmeric powder and fresh root for inflamation,
    for further pain relief look at dandelion, also ths/cbd

  • Would it be possible to change to another Doctor that would prescribe you the oxynorm instead of going back to the doctor that does not listen?

  • When doctors and nurses quite conderdicting each other and truth be told..my doctor let the receptionist scream across the lobby,my test results,true he wouldn’t say a word to me all is fine….they seperated. My son and I because we were both sick they kept him and told me to leave hospital.great doctor and nurses we have…they refused to help the sick…I’ve never seen him since…I’m very sick and have been that’s my story…

  • My best friend has Spina Bifida and she is having very similar issues to you regarding pain, meds, dismissive doctors, incompetent mistakes and waiting lists and of course the cruel welfare changes which have seen her loose her pip completely,so I truly empathise. Her experience as she’s got older ( shes now 54 ) is that all the brilliant spina bifida specialists she used to see when she was younger have now retired and because spina bifider is now rare in new births, Very few doctors want to specialise in the condition now so the doctors she has to see for the numerous difficulties she has are unabable to join the dots and understand the mechanics of her disability in it’s entirety. I’m so angry that you’ve had to go through all this crap in your life and especially having the dwp stuff on top, adding insult to injury. Please make sure you take care during this corona virus stuff. I don’t suppose you feel like doing a natural medicinal garden vid.? like a square foot garden but with medicinal plants. I was thinking of tring to start one as i have fibromyalgia which causes chronic pain and take zapain like smarties amongst other stuff they have me on but i don’t know where to begin with it.

  • I came to Project Diaries for some basic gardening info and while browsing the latest videos came across this. I’m very sorry. I hope you will get better soon. What’s happening to public healthcare in the UK is atrocious. I had no idea it was this bad. This is a human rights issue as it is.