Dr. Susan Harvey, Director of the Johns Hopkins Breast Imaging Section, discusses the role of Magnetic Resonance (MR) in breast imaging and the criteria to consider when ordering an MR of the breast.
Breast MRI and the role it plays in screening women who are high risk for breast cancer is the topic of conversation with Dr. Jay K. Harness, medical director of BreastCancerAnswers.com, and Dr. Ismail Jatoi, professor at University of Texas, San Antonio, at the 2012 San Antonio Breast Cancer Symposium.. The live broadcast was sponsored by Genomic Health, the creator of Oncotype DX. Genomic Health is a global healthcare company that provides actionable genomic information to personalize cancer treatment decisions. For more information, visit:. www.genomichealth.com
The study finds that abbreviated MRIs spotted more than twice as many cancers as the current gold standard, a 3D mammogram.. Subscribe to WCVB on YouTube now for more: http://bit.ly/1e8lAMZ. Get more Boston news: http://www.wcvb.com. Like us: https://www.facebook.com/wcvb5. Follow us: https://twitter.com/WCVB. Instagram: https://www.instagram.com/wcvb5/
Our own Kristyn Hartman, a breast cancer survivor, wanted to find out if a breast MRI could provide more accurate results for women than a mammogram. Here’s what she learned.
Dr. Stephen Edge, Chair of Breast Oncology and Director of the Breast Center at Roswell Park, addresses a question about the use of MRI, or magnetic resonance imaging, for the detection of breast cancer.
Learn about Breast MRIs for newly diagnosed women. We help you identify if you at High Risk and would benefit from annual screening MRIs.. VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:. http://www.breastcancercourse.org. LIST OF QUESTIONS FOR YOUR DOCTORS: http://www.breastcancercourse.org/breast-health-updates-latest-videos/. FOLLOW US: Facebook: https://www.facebook.com/Breast-Cancer-School-for-Patients-958519147618444/. _ Questions for your Breast Surgeon: 1. Will you order a Breast MRI to look for other tumors? 2. Could a Breast MRI change our treatment plans? 3. Do I qualify for a “Screening Breast MRI?”. 4. What are the disadvantages of a Breast MRI? 5. What are the benefits of Breast MRIs in newly diagnosed women? By the time someone has had a biopsy showing cancer, they likely have already had a mammogram and possibly a breast ultrasound. Once diagnosed, a “Pre-operative Breast MRI” can sometimes show other cancers that have yet to be identified by mammography or a physician’s breast examination. A Breast MRI can also provide more information about the tumor’s size and involvement of other structures such as the muscle or skin.. . When used before surgery (pre-operatively), Breast MRIs identify additional cancers in the same breast in about 16% of women and can find previously unknown cancers in the opposite breast in 3 to 5%. The findings from a pre-operative Breast MRI can change the surgical plans to treat your breast cancer. Breast MRIs are commonplace today and ordered by breast surgeons. Ask your surgeon if you would benefit from a Breast MRI before your surgery.. . Why a “Screening Breast MRI” for women at “High Risk?”. Women identified to be a very high risk of developing breast cancer should consider an annual screening Breast MRI in addition to their annual mammogram, according to recommendations (here) by the American Cancer Society. Together, these two screening tests give doctors a better chance of finding breast cancer in high risk women when the cancer is smaller, easier to treat, and easiest to cure.. . Consider a “Screening Breast MRI” if: You are a BRCA1 or BRCA2 mutation carrier. You have a first-degree relative (parent, sibling, child) with a BRCA1 or BRCA2 mutation, even if you have yet to be tested yourself. Your lifetime risk of breast cancer has been scored at 20 to 25% or greater, based on one of several accepted risk assessment tools that look at family history and other factors such as a biopsy showing Atypical Ductal Hyperplasia (ADH), Atypical Lobular Hyperplasia (ALH), and Lobular Carcinoma In-Situ (LCIS). You had radiation therapy to the chest for cancer (usually lymphoma) treatment between the ages of 10 and 30. . What are the downsides of a Breast MRI? If a breast MRI identifies a suspicious area in the breast, it may require a needle guided breast biopsy. Most of these additional biopsies prove to be benign, and can result in further imaging, anxiety, discomfort, and cost. In other words, Breast MRIs can lead to breast biopsies that might be considered unnecessary.. . There is also evidence to suggest that women who undergo a pre-operative Breast MRI for cancer are more likely to choose to have a mastectomy than those who do not have a Breast MRI. Some leading physicians argue that Breast MRIs lead to unnecessary mastectomies without improvements in cancer outcomes. (see below reference) Ultimately, the choice of having a mastectomy is based on your unique breast cancer situation and your personal priorities.. . Should I have a pre-operative Breast MRI? Most importantly, speak with your breast surgeon. Ask specifically what the advantages and disadvantages are for your unique situation. Over the last decade, more and more pre-operative Breast MRIs are being performed. This trend will likely continue as breast surgeons seek more information before making surgical treatment decisions.. . Those that benefit most from a pre-operative breast MRI are women younger than 50 years old, those with dense breasts, and BRCA mutation carriers. Ask your surgeon if your biopsy report also shows several high risk findings such as Atypical Ductal Hyperplasia (ADH), Atypical Lobular Hyperplasia (ALH), and Lobular Carcinoma In-Situ (LCIS). If your cancerous breast biopsy also showed these High Risk findings, then you benefit more from a pre-operative Breast MRI. You would likely also qualify for annual screening Breast MRIs in the years to come after your treatment if you are deemed at high risk and have a lumpectomy.. . What is the take-home message? In general, most breast surgeons feel pre-operative Breast MRIs are a good idea unless someone is elderly or extremely claustrophobic and would not tolerate the confined space of the MRI machine. If your breast surgeon never mentions a pre-operative Breast MRI as an option, you should inquire to become better informed.
Right now, the American Cancer Society recommends that MRI be used along with standard mammograms when women have a roughly 20 percent or higher lifetime risk of breast cancer. The average U.S. The technical term for the MRI finding is “background parenchymal enhancement.” If it does, in fact, foretell a particularly high risk of breast cancer, that could help women and their doctors make some choices, Rahbar said. Those women might want to be screened more often, or consider starting the drug tamoxifen, which cuts breast cancer risk. The technical term for the MRI finding is “background parenchymal enhancement.” If it does, in fact, foretell a particularly high risk of breast cancer, that could help women and their doctors make some choices, Rahbar said. Those women might want to be screened more often, or consider starting the drug tamoxifen, which cuts breast cancer risk.
The technical term for the MRI finding is “background parenchymal enhancement.” If it does, in fact, foretell a particularly high risk of breast cancer, that could help women and their doctors make some choices, Rahbar said. Those women might want to be screened more often, or consider starting the drug tamoxifen, which cuts breast cancer risk. Although mammography screening has been considered the mainstay of breast cancer screening, it has its limitations, especially for high-risk women. MRI, on the other hand, poses no risk of radiation-induced cancer and exhibits high sensitivity, and the potential risks from the application of gadolinium-containing contrast media are minimal.
Researchers found that among high-risk women who had MRI screening, those with a particular feature in the scans — namely, areas of background breast tissue that appear white — were nine times more likely to develop breast cancer over the next couple of years. MRI might predict cancer before it starts Their study suggests that breast MRI, a technique commonly used for screening high-risk women, could be used not only to catch breast cancer, but to predict it before it starts. Breast magnetic resonance imaging (MRI) is recognized as the most sensitive imaging method for the early detection of breast cancer. Therefore, women at a lifetime risk for breast cancer development of ≥ 20% are invited for intensified screening programs including both mammography and breast MRI. For most women, routine MRI screening would mean many unnecessary biopsies and a lot of unnecessary anxiety.
It’s a different story for women whose family histories or genetic inheritance put them. Clinicians currently rely on epidemiologic models to predict breast cancer risk. The most common is the GAIL model, which looks at a number of factors including a woman’s current age, the age she.
List of related literature:
Breast MRI was recommended for women with a greater than or equal to 20%–25% lifetime risk of developing breast cancer, including women with a known BRCA1 or BRCA2 mutation, a strong family history of breast or ovarian cancer, or a prior history of radiation therapy to the chest for the treatment of lymphoma.
High-risk women include BRCA1, BRCA2, TP53 and other high-risk mutation carriers, their first-degree relatives and women from untested families with a 20–30% lifetime breast cancer risk; annual MRI screening should be offered to them.
Screening MRI is recommended for women with an approximately 20% to 25% or greater lifetime risk of developing breast cancer, including women with a strong family history of breast or ovarian cancer and women who were treated for Hodgkin’s disease.
Although an average 35-year-old woman would have a 1/10,000 chance of having a cancer, a mutation carrier would have a risk in the range of 1 to 5/100, and MRI would be much more sensitive in this population than mammography.
In women at high risk (Box 40.1), MRI has been shown to have a high sensitivity for detection of malignancy particularly in women younger than 40 years.
A recent multiinstitutional study conducted by Lehman, et al. [67] concluded that women at high risk for breast cancer would benefit from screening MRI.
The American Cancer Society recommends screening MRI for women who have an approximately 20% to 25% or greater lifetime risk of breast cancer,115 but there are no published data regarding the use of MRI to diagnose breast cancer during pregnancy.
Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.
I have to get one soon. I’m 21, I had a mammogram/ultrasound and it came back unclear in my left breast. I have nipple discharge and pain on both breast. I have a family history of breast cancer too, I’m just super uneasy.
If your identical twin sister has breast cancer at 32 but does not carrie the gene that cause breast cancer, does that still count as family history or puts me at even higher risk for having breast cancer in my life time?
=✈ Cancer is a disease, a chronic metabolic disease akin to other chronic metabolic diseases such as scurvy, night blindness, pellagra & pernicious anemia. No such disease has ever been cured through mechanical manipulation of the body. Where cancer is seated isn’t relevant to its cure. The preventative, cure & treatment of this vitamin-deficiency disease is Amygdalin (vitamin B17). People who get at least 100 m.g. of B17 daily cannot contract cancer.
There is only one reason to do an MRI before a lumpectomy and that is if there is statistical evidence that this specific MRI captures more cancer cells than would have been taken out with just a lumpectomy. I cant take it for granted when a MRI manufacturer and a surgeon says its a good idea. Your video is very instructive Doc, but please give us numbers too.
Hi doc,I’m just watching this video about MRI.i had my first breast surgery October 25,2019.and I have the result Nov 4,2019,they diagnosed me an early BC stage 1 ER positive.i was shock and feeling depress.the next one is MRI Nov 25,2019 they found out both of my breast has tiny lump. And now I’m gonna undergo MRI Biopsy both breast again..I’m so scared to do it,like when I found out that I have another lump in my both breast soo scared to do the the biopsy Doc..ryt now I’m having anxiety and depress..
Implants of any type, either saline or silicone are a big mistake. My wife has lived with a deflated POS saline implant for the last 10 years. It began leaking less than a year after it was implanted. The site on her back where tissue was removed to use to support the implant is also a constant problem. Her surgeon should be horse whipped. Whatever happened to ” first do no harm?”
I’m having a small three pea size lump on my left breast. Do u think should go for MRI? I’m 18 preparing for my exam right now and I don’t want to hear that I’m cancer positive before or during the exam can I go to the doctor only after one month from now. Will it be too late? None of my family or relative have breast cancer.
I have dense breasts and have had a recurring left breast “knot”. My “lumpy” breasts tissue seems to allow my doctor to act more passively, when I feel like it should make him look more closely. He ordered an MRI last year and Blue Cross turned down coverage. Now this thing is back. I imagine it may be nothing while it could be DIC in early stages. I have a friend who was in same exact situation. He doc kept saying “normal” that her breasts were just “dense” and “lumpy”. She pressed on for MRI, was turned down. Six months later she felt a lump. She daw her doctor again, they were able to get the MRI confirming ductal carcinoma which had spread to several lymph nodes. She went thru hell; Red devil chemothe worst but she is ALIVE! I believe in taking charge of your own healthcare. We know our bodies and when something isn’t right. Doctors do their best most times but mammography isn’t fool proof. Keep pushing if you don’t feel comfortable. I am getting another opinion!
i had a mammogram and sonogram today. Which came up negative. I am being sent for an MRI I have a dent or dimple on my left breast. I have dense tissue. I’m 55. I recently lost 25 pounds. That is when I noticed this indentation in my breast.
I have to get one soon. I’m 21, I had a mammogram/ultrasound and it came back unclear in my left breast. I have nipple discharge and pain on both breast. I have a family history of breast cancer too, I’m just super uneasy.
If your identical twin sister has breast cancer at 32 but does not carrie the gene that cause breast cancer, does that still count as family history or puts me at even higher risk for having breast cancer in my life time?
=✈ Cancer is a disease, a chronic metabolic disease akin to other chronic metabolic diseases such as scurvy, night blindness, pellagra & pernicious anemia. No such disease has ever been cured through mechanical manipulation of the body. Where cancer is seated isn’t relevant to its cure. The preventative, cure & treatment of this vitamin-deficiency disease is Amygdalin (vitamin B17). People who get at least 100 m.g. of B17 daily cannot contract cancer.
There is only one reason to do an MRI before a lumpectomy and that is if there is statistical evidence that this specific MRI captures more cancer cells than would have been taken out with just a lumpectomy.
I cant take it for granted when a MRI manufacturer and a surgeon says its a good idea. Your video is very instructive Doc, but please give us numbers too.
Hi doc,I’m just watching this video about MRI.i had my first breast surgery October 25,2019.and I have the result Nov 4,2019,they diagnosed me an early BC stage 1 ER positive.i was shock and feeling depress.the next one is MRI Nov 25,2019 they found out both of my breast has tiny lump.
And now I’m gonna undergo MRI Biopsy both breast again..I’m so scared to do it,like when I found out that I have another lump in my both breast soo scared to do the the biopsy Doc..ryt now I’m having anxiety and depress..
Implants of any type, either saline or silicone are a big mistake. My wife has lived with a deflated POS saline implant for the last 10 years. It began leaking less than a year after it was implanted. The site on her back where tissue was removed to use to support the implant is also a constant problem. Her surgeon should be horse whipped. Whatever happened to ” first do no harm?”
They need to see in some cases 3d printing it even with ovarion cancer as the machine prints it be able to stop the machine so you have a inside view
I’m having a small three pea size lump on my left breast. Do u think should go for MRI? I’m 18 preparing for my exam right now and I don’t want to hear that I’m cancer positive before or during the exam can I go to the doctor only after one month from now. Will it be too late?
None of my family or relative have breast cancer.
I have dense breasts and have had a recurring left breast “knot”. My “lumpy” breasts tissue seems to allow my doctor to act more passively, when I feel like it should make him look more closely. He ordered an MRI last year and Blue Cross turned down coverage.
Now this thing is back. I imagine it may be nothing while it could be DIC in early stages. I have a friend who was in same exact situation. He doc kept saying “normal” that her breasts were just “dense” and “lumpy”. She pressed on for MRI, was turned down. Six months later she felt a lump. She daw her doctor again, they were able to get the MRI confirming ductal carcinoma which had spread to several lymph nodes. She went thru hell; Red devil chemothe worst but she is ALIVE! I believe in taking charge of your own healthcare. We know our bodies and when something isn’t right. Doctors do their best most times but mammography isn’t fool proof. Keep pushing if you don’t feel comfortable. I am getting another opinion!
i had a mammogram and sonogram today. Which came up negative. I am being sent for an MRI I have a dent or dimple on my left breast. I have dense tissue. I’m 55. I recently lost 25 pounds. That is when I noticed this indentation in my breast.