Is Gestational Diabetes Associated with Autism

 

Is There A Connection Between Gestational Diabetes and Autism?

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Maternal Diabetes and Autism in Offspring

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Scientists Find Link Between Gestational Diabetes And Autism

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Dr. Max Gomez: Gestational Diabetes And Autism

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Maternal Diabetes and Autism

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Is there a link between gestational diabetes and autism?

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Maternal Diabetes Linked to Autism Risk

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The blood sugar disorder, known as gestational diabetes, was linked to a moderately increased risk for an autism spectrum disorder in a study of more than 320,000 U.S. children, said study. TUESDAY, April 14, 2015 (HealthDay News) Pregnancy-related diabetes may increase the risk a child will develop autism, new research suggests. The blood sugar disorder, known as gestational diabetes, was linked to a moderately increased risk for an autism spectrum disorder in a study of more than 320,000 U.S. children, said study researcher Anny Xiang, director of statistical research at Kaiser. The blood sugar disorder, known as gestational diabetes, was linked to a moderately increased risk for an autism spectrum disorder in a study of more than 320,000 U.S. children, said study.

TUESDAY, April 14, 2015 (HealthDay News) Pregnancy -related diabetes may increase the risk a child will develop autism, new research suggests. The blood sugar disorder, known as gestational diabetes, was linked to a moderately increased risk for an autism spectrum disorder in a study of more than 320,000 U.S. children, said study researcher Anny Xiang, director of statistical research at Kaiser. Nor were they women who got gestational diabetes after 26 weeks.

Instead, the link between early gestational diabetes and an increased likelihood of autism diagnosis could mean that a fetus’ early exposure to uncontrolled high blood sugar may somehow affect brain development. Researchers found that mothers-to-be who developed gestational diabetes — high blood sugar during pregnancy in women who have never had diabetes — by their 26th week of pregnancy were 63. Maternal gestational diabetes linked to autism risk for offspring A team of researchers states that intrauterine exposure to gestational diabetes mellitus is associated with an increased risk of. “Children born to mothers with gestational diabetes are at risk for diabetes themselves, obesity, and through this evidence, autism,” says Alycia Halladay, PhD, chief science officer of the Autism Science Foundation.

Developing gestational diabetes before week 26 of pregnancy can increase the baby’s risk of autism. Autism has previously been linked to type 2 diabetes and to gestational diabetes — a temporary condition in which a woman develops diabetes during the course of her pregnancy. One of the new studies confirms these risks and extends the link to type 1, or juvenile, diabetes, the most severe form of the condition.

Researchers at the University of California Davis have given mothers with type 2 diabetes or gestational diabetes something else to worry about. They.

List of related literature:

Gestational diabetes also increases the risk of autism (Xiang et al., 2015), as does exposure to abuse from an intimate partner within two years prior to the birth year (Roberts et al., 2016).

“The Environmental and Genetic Causes of Autism” by James Lyons-Weiler
from The Environmental and Genetic Causes of Autism
by James Lyons-Weiler
Skyhorse, 2016

The caudal regression syndrome has also been reported to be much more frequent in diabetic compared with nondiabetic pregnancies, so the risk of that rare abnormality is likely to be increased by maternal pregestational diabetes as well.

“Diabetes in America” by National Diabetes Data Group (U.S.), National Institute of Diabetes and Digestive and Kidney Diseases (U.S.), National Institutes of Health (U.S.)
from Diabetes in America
by National Diabetes Data Group (U.S.), National Institute of Diabetes and Digestive and Kidney Diseases (U.S.), National Institutes of Health (U.S.)
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 1995

However, in women who do not reach diabetes diagnostic criteria, there is mounting evidence that increasing BMI causes higher glucose levels, which in pregnancy are associated with adverse outcomes (49).

“Oxford Textbook of Obstetrics and Gynaecology” by Sabaratnam Arulkumaran, William Ledger, Stergios Doumouchtsis, Lynette Denny
from Oxford Textbook of Obstetrics and Gynaecology
by Sabaratnam Arulkumaran, William Ledger, et. al.
Oxford University Press, 2019

It is estimated that 3% to 25% of a population of pregnant women will be diagnosed with GDM.22 This is not surprising, because GDM is the precursor to T2DM for many women, based on ethnicity-specific increases in insulin resistance and rising obesity in women of reproductive age.

“Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice” by Robert Resnik, MD, Robert K. Creasy, MD, Jay D. Iams, MD, Charles J. Lockwood, MD, MHCM, Thomas Moore, MD, Michael F Greene, MD
from Creasy and Resnik’s Maternal-Fetal Medicine: Principles and Practice
by Robert Resnik, MD, Robert K. Creasy, MD, et. al.
Elsevier Health Sciences, 2013

Maternal glucose intolerance is becoming identified as a teratogen regardless of whether the mother has diabetes mellitus or is identified at 28 weeks to have gestational diabetes during gestation.

“Developmental-Behavioral Pediatrics E-Book” by William B. Carey, Allen C. Crocker, Ellen Roy Elias, Heidi M. Feldman, William L. Coleman
from Developmental-Behavioral Pediatrics E-Book
by William B. Carey, Allen C. Crocker, et. al.
Elsevier Health Sciences, 2009

The risk for congenital anomalies is not increased in most pregnancies with GDM.154 However, in GDM with fasting hyperglycemia that is diagnostic of DM, there is an increased risk for birth defects that is proportional to the severity of the hyperglycemia.

“Endocrinology: Adult and Pediatric E-Book” by J. Larry Jameson, Leslie J. De Groot
from Endocrinology: Adult and Pediatric E-Book
by J. Larry Jameson, Leslie J. De Groot
Elsevier Health Sciences, 2015

Infants born to mothers with gestational diabetes have a higher risk for developing childhood obesity, gestational diabetes, type 2 diabetes, and metabolic syndrome.28 We can even see these changes on a molecular level.

“Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome” by Debasis Bagchi, Sreejayan Nair
from Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome
by Debasis Bagchi, Sreejayan Nair
Elsevier Science, 2012

Additionally, if mothers had at least one of several medical conditions—diabetes (type 2 or gestational), chronic hypertension, or prepregnancy obesity—this was correlated with a 60% increased risk for autism and a 150% increased risk for developmental delay (Krakowiak et al., 2012).

“Child Psychopathology, Third Edition” by Eric J. Mash, Russell A. Barkley
from Child Psychopathology, Third Edition
by Eric J. Mash, Russell A. Barkley
Guilford Publications, 2014

However, the recent dramatic increase in type 2 diabetes prevalence has led to the recommendation that high-risk women found to have diabetes at their initial prenatal visit receive a diagnosis of overt diabetes.88 GDM complicates approximately 7% of all pregnancies.

“Pathophysiology: The Biologic Basis for Disease in Adults and Children” by Kathryn L. McCance, RN, PhD, Sue E. Huether, RN, PhD
from Pathophysiology: The Biologic Basis for Disease in Adults and Children
by Kathryn L. McCance, RN, PhD, Sue E. Huether, RN, PhD
Elsevier Health Sciences, 2014

Maternal diabetes has not been found to be a risk factor for the development of autism (Hultman, Sparen and Cnattingius 2002).

“An A-Z of Genetic Factors in Autism: A Handbook for Parents and Carers” by Kenneth Aitken
from An A-Z of Genetic Factors in Autism: A Handbook for Parents and Carers
by Kenneth Aitken
Jessica Kingsley Publishers, 2011

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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  • So does that mean that all the women with gestational diabetes got it from their vaccines?
    It all makes sense now…vaccines = diabetes = autism. Spread the word!!!