Gene Test May Allow Many With Early Cancer Of The Breast to prevent Chemotherapy

 

Nearly 70 percent of early breast cancer patients may not need chemotherapy: Study

Video taken from the channel: ABC News


 

Gene Tests Can Help Breast-Cancer Patients Avoid Chemotherapy, Study Says

Video taken from the channel: CBS Los Angeles


 

Genetic Breast Cancer Test Helps Some Patients Avoid Chemo

Video taken from the channel: OhioHealth


 

Most women with smaller breast cancer tumors can safely skip chemo, study finds

Video taken from the channel: PBS NewsHour


 

Comment: Genetic testing of early breast tumours could allow patients to go without chemo

Video taken from the channel: ecancer


 

Gene test spares cancer patient from chemo

Video taken from the channel: ABC Action News


 

More women with early breast cancer can avoid chemo, study finds

Video taken from the channel: CBS This Morning


SUNDAY, June 3, 2018 A majority of women with an early form of a common breast cancer may be able to skip chemotherapy, depending on the results of a comprehensive gene test. The new study of nearly 7,000 women found that use of the already available Oncogene DX gene test could pinpoint those women who needed chemotherapy, and those who did not. HealthDay Reporter SUNDAY, June 3, 2018 (HealthDay News) A majority of women with an early form of a common breast cancer may be able to skip chemotherapy, depending on the results of a. SUNDAY, June 3, 2018 (HealthDay News) A majority of women with an early form of a common breast cancer may be able to skip chemotherapy, depending on the results of a comprehensive gene test. The new study of nearly 7,000 women found that use of the already available Oncogene DX gene test could pinpoint those women who needed chemotherapy, and those who did not.

SUNDAY, June 3, 2018 (HealthDay News)—A majority of women with an early form of a common breast cancer may be able to skip chemotherapy, depending on the results of a comprehensive gene test. The new study of nearly 7,000 women found that use of the already available Oncotype DX gene test could pinpoint those women who needed chemotherapy, and those who did not. bc-US-breast-cancer-gene-test SUNDAY, June 3, 2018 A majority of women with an early form of a common breast cancer may be able to skip chemotherapy, depending on the results of a comprehensive. Nearly half of early breast cancer cases that meet traditional criteria for high risk can be treated just as effectively without chemotherapy as with it, according to the study, which used genetic. Chemotherapy use for women with early-stage breast cancer had been declining in recent years due to more widespread use of the 21-gene test.

With this new evidence, even more women can be spared. Ongoing clinical trials are also exploring the usefulness of this test for women whose breast cancer has spread to the lymph nodes in the underarm. Reese was diagnosed with Stage 2 breast cancer. A gene test showed a low risk of recurrence, so after being treated with radiation therapy, she didn’t need chemotherapy. “I did the right thing,”.

The study therefore can’t say whether skipping chemo based on a genetic test makes it more likely that early breast cancer will spread six, 10, 15, or more years later. Many Women Can Skip Chemo for Early-Stage Breast Cancer. Doctors used a genomic test (Oncotype DX) that looks at 21 genes to determine each woman’s risk of recurrence on a scale of 0 to 100.

List of related literature:

The genetic test is positive for gene BRCA1, and her risk of breast cancer is significantly higher thanfor other women who do not have this gene.

“Health & Wellness”
from Health & Wellness
by
, 2008

Overall, the prevalence of germline p53 mutations in women diagnosed with breast cancer younger than 40 years is 1%, thus limiting the widespread application of p53 for screening breast cancer.”

“Surgery: Basic Science and Clinical Evidence” by Jeffrey Norton, R.Randall Bollinger, Alfred E. Chang, Stephen F. Lowry
from Surgery: Basic Science and Clinical Evidence
by Jeffrey Norton, R.Randall Bollinger, et. al.
Springer Berlin Heidelberg, 2012

In addition to breast cancer, mutations in the BRCA1 gene also increase the risk of ovarian, fallopian tube, and prostate cancers.

“Smart Study Series:Obstetrics & Gynecology E-Book” by PUNIT S BHOJANI
from Smart Study Series:Obstetrics & Gynecology E-Book
by PUNIT S BHOJANI
Elsevier Health Sciences, 2014

In fact, a 1997 study showed the risk of breast cancer for variations on the BRCA1 gene to be closer to 56 percent, and only 16 percent for ovarian cancer.

“Goddesses Never Age: The Secret Prescription for Radiance, Vitality, and Well-Being” by Christiane Northrup, M.D.
from Goddesses Never Age: The Secret Prescription for Radiance, Vitality, and Well-Being
by Christiane Northrup, M.D.
Hay House, 2015

Widespread screening for BRCA1 or BRCA2, inherited mutations that increase the risk for breast cancer, is not recommended, but women with a suggestive family history (multiple first-degree relatives with breast or ovarian cancer) should be referred for genetic counseling.

“Goldman's Cecil Medicine,Expert Consult Premium Edition Enhanced Online Features and Print, Single Volume,24: Goldman's Cecil Medicine” by Russell La Fayette Cecil, Lee Goldman, Andrew I. Schafer
from Goldman’s Cecil Medicine,Expert Consult Premium Edition Enhanced Online Features and Print, Single Volume,24: Goldman’s Cecil Medicine
by Russell La Fayette Cecil, Lee Goldman, Andrew I. Schafer
Elsevier/Saunders, 2012

Screening for mutations in these genes can provide a risk-alerting system for breast and ovarian cancer.

“Introduction to Genomics” by Arthur M. Lesk
from Introduction to Genomics
by Arthur M. Lesk
Oxford University Press, 2017

Detectable mutations in the BRCA1 and BRCA2 genes account for 90% of ovarian cancers in the Hereditary Breast and Ovarian Cancer syndrome, and up to 85% of all familial ovarian cancers.

“Diagnostic Pathology of Ovarian Tumors” by Robert A. Soslow, Carmen Tornos
from Diagnostic Pathology of Ovarian Tumors
by Robert A. Soslow, Carmen Tornos
Springer New York, 2011

Taken together, our results show that 5% of Asian breast cancer patients have pathogenic mutations in BRCA1 or BRCA2, and that germline testing can be cost­effectively delivered to Asian women by focusing primarily on women with early onset breast cancer in the presence of family history of breast and ovarian cancers.

“AACR 2017 Proceedings: Abstracts 3063-5947” by American Association for Cancer Research
from AACR 2017 Proceedings: Abstracts 3063-5947
by American Association for Cancer Research
CTI Meeting Technology, 2017

Mutations in certain known genes such as BRCA1 and BRCA2, which are also a risk factor for ovarian cancer, account for less than 10 percent of breast cancers.

“Diseases and Disorders” by Marshall Cavendish Corporation
from Diseases and Disorders
by Marshall Cavendish Corporation
Marshall Cavendish, 2007

The BRCA1 gene accounts for a small percentage of breast cancers, primarily in families in which cancer onset occurs at a young age, and genetic testing of all persons at risk for breast cancer is not warranted.

“Robbins and Cotran Review of Pathology” by Edward C. Klatt, MD, Vinay Kumar
from Robbins and Cotran Review of Pathology
by Edward C. Klatt, MD, Vinay Kumar
Elsevier Health Sciences, 2014

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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  • Well im working on some cures for alot of diseases mental issues u name it and i was happy to here this what i came to the conclusion with breast cancer my ladies are vulnerable when lactating and pesticides and cancer causing chems are exposed and bras are like sponges triggered it kind of like cucu clock where they bathed it in mercury some antiques in peoples houses may have shit they used back in the day thats poisonous im looking into this taxidermy as well cause they also use some wicked chems and people have this stuff in there house that may be causing health and mental issues i did look into this make up as well so how they get you is antioxidants in the make up passes regulations then what happens you give maybe to your daughter for example trying to cover her pimples and in draws out the toxins in her face creating a cycle of buying more and more of the product to cover it and others to fix the acne problem so then it makes me wonder are the dermatologist have role in this as well cause thats some dirty shit and yes I see very clearly i can end world hunger as well asian fish explosion gather the kids we going fishing plant some of these fish grow crops send them to some starving places around the world and some seeds id also be lowering global warming working on world peace as well i see these noble prizes are set up for some like me i make it look easy