Checking Bloodstream for Coronavirus Antibodies 3 Questions Clarified About Serological Tests and Immunity

 

Beaumont launches nation’s largest serological testing study for COVID-19 antibodies

Video taken from the channel: Beaumont Health


 

Serologic Testing: How Does Antibody Testing Work?

Video taken from the channel: Penn Medicine


 

UW Medicine to perform diagnostic blood tests for past COVID-19 infections

Video taken from the channel: UW Medicine


 

Serologic Testing: What Are Antibodies?

Video taken from the channel: Penn Medicine


 

Everything You Need to Know About Antibody Testing for COVID-19

Video taken from the channel: Johns Hopkins Bloomberg School of Public Health


 

COVID-19: Antibody Testing: Your Questions Answered

Video taken from the channel: Loyola Medicine


 

Mayo Clinic expert answers questions about antibody testing for COVID-19

Video taken from the channel: Mayo Clinic


Checking blood for coronavirus antibodies – 3 questions answered about serological tests and immunity Aubree Gordon, Professor of Public Health, University of Michigan and Daniel Stadlbauer, Postdoctoral Fellow in Microbiology, Icahn School of Medicine at Mount Sinai. Checking blood for coronavirus antibodies – 3 questions answered about serological tests and immunity clarisezoleta Courtesy of Aubree Gordon, University of. Checking blood for coronavirus antibodies – 3 questions answered about serological tests and immunity Coronavirus testing in the United States is moving into a new phase as scientists begin looking. Checking Blood for Coronavirus Antibodies – 3 Questions Answered About Serological Tests and Immunity Coronavirus testing in the United States is moving into a new phase as scientists begin looking into people’s blood for signs they’ve been infected by SARS-CoV-2, the virus that causes COVID-19. Coronavirus testing in the United States is moving into a new phase as scientists begin looking into people’s blood for signs they’ve been infected by SARS-CoV-2, the virus that causes COVID-19.

This technique is called serological testing. CDC has a strategy for using antibody testing as part of surveillance efforts to better understand how much of the U.S. population has been infected with SARS-CoV-2 and how the virus is spreading through the population over time. Learn more about CDC’s COVID-19 serology surveillance strategy. Checking blood for coronavirus antibodies – 3 questions answered about serological tests and immunity Aubree Gordon, University of Michigan and Daniel Stadlbauer, Icahn School of Medicine at. Antibody tests can’t be used to diagnose the new coronavirus (COVID-19), but they can tell you if you’ve ever had it.

This can help health officials understand and fight the virus. Learn more. “Serologic testing is one of the most powerful tools we have not for day-to-day testing, but to understand where the immunity gaps are and where there are a.

Coronavirus antibody tests also known as serology tests aren’t meant to diagnose active infection. The test checks whether a person has developed antibodies against the coronavirus, which.

List of related literature:

Other tests to consider include antinuclear antibody (ANA), extractable nuclear antigens (ENA), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), anti-skin antibodies, HIV and mycoplasma serology.

“Textbook of Adult Emergency Medicine E-Book” by Peter Cameron, Mark Little, Biswadev Mitra, Conor Deasy
from Textbook of Adult Emergency Medicine E-Book
by Peter Cameron, Mark Little, et. al.
Elsevier Health Sciences, 2019

Antibodies to a chloroformmethanol glycolipid extract of M. pneumoniae are detected by a CF test in more than 85% of culture-positive patients; a single elevated titer of greater than 80 or a greater than fourfold rise in titer between acute and convalescent sera is required to establish a diagnosis.

“Murray & Nadel's Textbook of Respiratory Medicine E-Book” by Robert C Mason, John F. Murray, Jay A. Nadel, Michael B. Gotway, V.Courtney Broaddus, Joel D Ernst, Talmadge E King, Jr, Stephen C. Lazarus, Arthur Slutsky
from Murray & Nadel’s Textbook of Respiratory Medicine E-Book
by Robert C Mason, John F. Murray, et. al.
Elsevier Health Sciences, 2015

In diagnostic laboratories, these responses are measured using the complement fixation (CF) test for the short-lived (IgM) antibody response and the virus neutralization (VN) test for the longer-lived (IgG) antibody response.

“Equine Infectious Diseases E-Book” by Debra C. Sellon, Maureen Long
from Equine Infectious Diseases E-Book
by Debra C. Sellon, Maureen Long
Elsevier Health Sciences, 2013

Diagnosis is made by the presence of clinical manifestations plus a differential WBC count showing lymphocytes and monocytes more than 50%; a heterophil agglutination antibody test with an antibody titer greater than 1:40; and an EBV-immunoglobulin M test with antibodies more than 1:80.

“Mosby's Medical Dictionary E-Book” by Mosby
from Mosby’s Medical Dictionary E-Book
by Mosby
Elsevier Health Sciences, 2013

ASO, antistreptolysin titer; CBC, complete blood count; CMV, cytomegalovirus; CXR, chest radiograph; EBV, Epstein-Barr virus; ESR, erythrocyte sedimentation rate; PPD, purified protein derivative; VDRL, Venereal Disease Research Laboratory.

“Pediatric Surgery E-Book” by Arnold G. Coran, Anthony Caldamone, N. Scott Adzick, Thomas M. Krummel, Jean-Martin Laberge, Robert Shamberger
from Pediatric Surgery E-Book
by Arnold G. Coran, Anthony Caldamone, et. al.
Elsevier Health Sciences, 2012

• Blood studies show leukocytosis, elevated ESR, IgA, and IgG; low titer rheumatoid factor; circulating immune complexes: anti-neutrophil cytoplasmic antibody in more than 90% of clients.

“NCLEX-RN(R) Review Made Incredibly Easy!” by Lippincott, Williams
from NCLEX-RN(R) Review Made Incredibly Easy!
by Lippincott, Williams
Wolters Kluwer Health, 2012

Other tests confirm specific antibodies to bacterial or viral infections such as the heterophile antibody for infectious mononucleosis; viral hepatitis A, B, or C; or the Helicobacter antibody test.

“Iron Disorders Institute Guide to Anemia” by Cheryl Garrison
from Iron Disorders Institute Guide to Anemia
by Cheryl Garrison
Sourcebooks, Incorporated, 2009

Diagnosis A number of serologic markers (viral antigens and antibodies to the viral antigens) and nucleic acid testing are available to diagnose acute and chronic HBV infection.

“Conn's Current Therapy 2020, E-Book” by Rick D. Kellerman, KUSM-W Medical Practice Association, David Rakel
from Conn’s Current Therapy 2020, E-Book
by Rick D. Kellerman, KUSM-W Medical Practice Association, David Rakel
Elsevier Health Sciences, 2019

Serological diagnosis of acute IM is most accurately made by the presence of IgM anti-VCA and anti-EA antibodies and the absence of anti-EBNA antibodies.

“Postgraduate Haematology” by A. Victor Hoffbrand, Douglas R. Higgs, David M. Keeling, Atul B. Mehta
from Postgraduate Haematology
by A. Victor Hoffbrand, Douglas R. Higgs, et. al.
Wiley, 2016

The test is based on the observation that, during acute infection,IgG antibodies bind antigen weakly or have lowavidity, while patients with chronic infection have more stronglybinding (high­ avidity)antibodies.

“Manual of Clinical Microbiology” by James Versalovic
from Manual of Clinical Microbiology
by James Versalovic
ASM Press, 2011

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

View all posts

47 comments

Your email address will not be published. Required fields are marked *

  • How likely are you to be “positive” through the nasal swab if you are tested positive for having the antibodies/IGG/IGM? I’ve only been sick for roughly a week, and I’m feeling better now, but but today I was tested positive for the immunity test, but I have to wait for the swab test.

  • I have covid-19 antibodies and I recently got sick with the symptoms again. So I’m not sure if I am immune to the virus. I continue to feel lightheaded at the most. But I struggled with headaches everyday, heart palpitations, fainting, shortness of breath just walking from the bed to the bathroom. Covid-19 is real.

  • How far back can the anti body test go back
    I was really sick in January with all the symptoms of COVID-19 but never been tested at that time
    I did the anti body test in may but it was negative.
    Please advise

  • My wife and I got sick for about 20 days starting around March 5th this year. Neither of us got fever though (never even reached 37 degrees Celsius). But wer were getting chills, coughing (wet cough) and generally feeling crappy for this entire 20-day duration. But since everyone was instructed not to go to hospitals/see doctors unless they were “dying”, and also tests were still not available then; we never got tested for Covid19. So we don’t know if the coronavirus was our problem, or we were just “normally” ill. By the end of March we were both fine (it was, however, a very long period to be sick for). 
    So my question is, is there a way to test/find out now, whether we HAD been infected by the coronavirus back in March? (It would be GREAT to know, as that would probably mean that Covid19 probably won’t kill us in the future either unless a completely different strand of the virus comes along that would affect us differently and more importantly, we would now know if we are now more protected from Covid19 as we’ll assumably have antibodies against it now. At least against THIS strand/”iteration” of the virus..

    **Please only reply to this question if you actually KNOW the answer (no “assumptions” please!). 😉

  • I tested positive for corona in May. Yesterday (august) my antibody test was negative! I was super sick with COVID and now my body doesn’t have fighters for it? Can you explain? I don’t want to cough blood again

  • MAYO_We need a show about the Cell Mediated immunity system and T-cell release for those that want to verify their negative serological test! And would be great to know why the cells are not transplanted but only plasma. Could the T-cell defence not be transplanted as well? So whole blood transfusion instead of only plasma as that would cover B-cell antibodies including T-cell defence. Or are they included in the plasma already?

  • what would you do if your elisa based test was positive but your lateral flow based test was negative? the two tests taken within 2 days of one another.

  • How do we get tested for the immunity. I was sick when I flew back from lax and seattle the end of january,my cough lasted 7 weeks after. I live in mn.

  • Is a positive IGM or IGG in rapid antibody tests solely points to COVID 19 infection? Or does it point to other diseases as well?

  • The antibody test has a accuracy rate of 50% so 1 out of 2 could be false negative or positive because if you had a common cold which is caused by a different Coronavirus these test will show positive for that also. Until a test is 100% reliable I would not bother with any of this testing and certainly don’t pay for one of these test.

  • FALSE POSITIVES INFLATED CASE NUMBERS Dr Deborah Birx warned long
    ago and CDC have just now finally admitted it!
    “If you have 1% of the population infected and you have a test that is
    only 99% specific, then if you find a positive, then 50% of time it will
    be a real positive and 50% of time it won’t be! [ie, it will be a false
    positive]”.
    https://www.youtube.com/watch?v=GdN-11btc0&list=PLtoX6L88vjkeom-8rYnV_WlGJHumatZCT

  • My mom says she thinks I may have had the virus back in February. She thinks this because in the beginning of feb, I had pains in my chest every time I breathed. We went to the doctor, and they said I had ‘inflammation caused from a virus’ and yes, it could have been any virus, but it might have been corona.

  • Additional caution for those patients whose doctors have seen and treated patients where they believe the patient was infected with Covid19 and believe the test result is a false negative. There is now a 40% accuracy rate of Covid19 test which is the original test kit. The false negatives now are because that first kit isn’t picking up on the virus mutation!

  • https://www.gov.uk/guidance/high-consequence-infectious-diseases-hcid
    As of 19 March 2020, COVID-19 is no longer considered to be a high consequence infectious diseases (HCID) in the UK.

  • Relevant Rockefeller document
    https://www.academia.edu/42295029/Rockefeller_Vakf%C4%B1n%C4%B1n_May%C4%B1s_2010_Raporu_Scenarios_for_the_Future_of_Technology_and_International_Development_

  • And it only costs $139.00 ����You people are wanting to know how this virus has effected the world and are charging money for it when the feds are giving billions to fund things like this? Dont waste your money peoole!

  • My mom recently got hospitalized because of covid (pneumonia and tested positive). I went and got a test but I tested negative even though we live in the same house. I had what I thought were mild symptoms but the test contradicts it.

    Now I don’t know if I should go get another test or try for the antibodies.

  • I had all the symptoms in March! Got tested in May for both active virus and antibodies.Through a full lab work up blood draw. It was negative for active and negative for antibodies! IMPOSSIBLE. I had no smell, cough, headaches and sore throat and muscles. Fever and chills. Plus major stomach issues. I was sick for 2 weeks and then better. Then sick again after feeling well for 3 weeks or so. Sick again. I’ll say I got this around March 10, then again in April by May 5 tested negative for active, May 20th negative for antibodies. I guess I’m still waiting on my body to produce antibodies since March? Will I ever products something that says you had this. I’m waiting another month to do another antibody test. So where do they get a few days to weeks for the antibodies? I don’t think it’s full protection at all. Nothing has shown up, nothing? They say you never had this. No way is that correct or true! What is happening, IMPOSSIBLE LITERALLY IMPOSSIBLE! I know I had this, no smell or taste that was a bigggest sign! Plus, sick and well and sick again! I had a heart issue too. I got a PET scans May 21st yesterday. Waiting on that result. Something is wrong or to get true immunity it must take longer than expected times. It’s been 2 months on the short duration and nothing showed up. Any answers? PS I have ulcerated colitis does that make a difference?

  • Early on; January, February and March of 2020, “convalescent blood plasma transfusions” usually was concerning patients who were very ill with the caronavirus. Since then, most all of the tests I’ve seen say that the plasma transfusions are usually successful for anyone with caronavirus; especially if administered early on. If donor supply becomes widely available, why not administer the plasma as a common treatment? Seems to be something missing as far as the media not broadcasting the test results of plasma transfusion and that there is a lack of promoting blood transfusions.

  • WOW! I was thinking if doctors can tell a patient with antibodies how to prevent the disease; why can’t doctors create medicine to cure the patient when they get the disease? All they need is some drug that will allow an immune response against the virus. I discovered the drug monoclonal antibody. Maybe research can be done to see if this is the needful medicine. Thanks for your research.

  • You guys seem really stuck on people being exposed, having antibodies, but somehow NOT being immune! You keep saying you just don’t know yet and you don’t want people to think they’re immune when they might not be (even though they probably are). But if they have any amount of the right antibodies remember, THEY ALREADY BEAT THE VIRUS!! And they probably did it easily, without even realising they were sick. By the end of the video you sound like you are only looking for problems with this type of testing. Not once did you mention the potential positive (that is already being reported https://www.google.com/amp/s/www.nytimes.com/2020/04/23/nyregion/coronavirus-antibodies-test-ny.amp.html ) that these studies could lead to a a lifting of societal restrictions if they were to show a high prevalence that in turn would push the case fatality rate lower than it is currently believed to be, making Covid 19 not actually as dangerous as first thought. Why..?

  • My dr just had me take the Mayo antibody test yesterday. I don’t know the results yet. Can you tell me how accurate the antibody test is?

  • Couldn’t find the original post but crazy enough even with the sam exact Covid toes (measles like rash) it was negative. I was shocked.

  • I think I may of contracted COV19 I’m far better than I was a few weeks back so I may of got over the virus off if you want someone to get anti body’s from I’m more than willing to do what ever I can to help.

    I will be ordering a home test this week so will pop back and let you know the results.

    Tha k you for all of your hard work guys������

  • I hear more and more people reporting having a really elongated dry cough (4 weeks to 7 weeks) and then being recovered. What is the chance they were infected with covid19? Or ware they just symptomatic co-incidences??

  • The WHO says antibodies is not reliable to show immunity. That statement should throw there whole vaccine program in the trash. Isn’t that how they test to see if there vaccine is working? You get a shot then they test for antibodies! So they really don’t know if there vaccines work or not since antibodies is now not reliable way to test for immunity.  They are always putting their foot in their mouth they Lie so much they can’t keep it together. Like a child who tell a Lie then tell The truth because they forgot they told a lie to begin with. LOL,LOL their Vaccine empire is crumbling around them.
    No evidence antibody tests can show coronavirus @t › 2020/04/17 › who-issues-warning-on…

    WHO warning: No evidence that antibody tests can show coronavirus immunity. Published Fri, Apr 17 20201:38 PM EDT Updated Sun, Apr 19 202012:34 PM…

  • She is so beautiful. If i see her i will say “I love you”. I watch this video 10 times. What is her name?
    Please if you know her HONK me!!!!

  • You can’t check for something that doesn’t exist. Wake up people!!!! Don’t be sheeps sent for slaughter. Stop listening to bs mainstream media agenda. Its so clear to see what’s happening, truth is coming out. It’s for you to decide if you want see it.

  • Just a genuine question…forgive any ignorance…what if people like me who work with covid patients everyday, and have been exposed on many occasions yet haven’t tested positive get tested for antibodies?…

  • So i just received my antibody test from my Doc and it is positive at 7.4, my question is what is considered a high antibody count? I cant seem to find info on this and my doctor does not know the upper limit of this test. He just told me it was one of the highest from all the other patients he has tested. The test is from Abbott and all they say is <1.4 = negative, >1.4 positive. I even looked at there manual for the test and cant find any “upper limit”.

  • So, what you’re saying is, that Rhesus monkey’s have about 1 month immunity, but like the WHO said, there is no proof that having had COVID confers immunity to… humans.

  • NO offense, but the “experts” have been wrong about the virus since day 1. The data coming in is showing that the virus is far, far less deadly than the “experts” have been predicting.

  • I have proof this antibodies for covid lasts no more than three months, and last that what one family member has found. Full blood test not finger prick first in Sydney 26th August second in first week in June. The first showed antibodies, the second none at all. So if anyone has tested and had no antibodies,, they still might have had the virus but the antibodies, may not be present any more if it was early in the year.

  • Wake-up, people. The planet and our country have been shut down by hysteria and fear. Masks, social distancing, and contact-tracing are all SNAKE OILS being sold to us. Don’t buy into it. It is silly to be walking around wearing a mask and praying for a vaccine when we already have a cure. HCQ. HCQ is cheap, effective and has been in use for 70+ years. Big pharma and the medical mafia can’t make a dime on it so it must be shown to be “scary” so they can push the new expensive, patented, and exclusive drug and vaccines that will certainly have more risks. People, look at the fine print on all of the medications you take right now before you talk about the risks of taking HCQ as a preventative or cure.

  • I am enlightened during this ‘pandemic’. As a RN, the people in the streets yelling at medical professionals is the same treatment in the medical facilities. We are really learning who the takers and givers are in this age. I feel so bad for anyone under the age of 25. I can’t help but wonder what they are thinking.

  • How accurate are the antibody tests? Are they 70 percent accurate? 90? 99? Can any1 tell me as ive heard we have alot of coronaviruses in our body already

  • If you have had contracted it but had no symptoms but did lose your antibodies (immunity) why would it affect your body any worse if you contracted it again??

  • What I want to find is where in Oregon clinics or facilities are offering the serology samples to be taken for the Mayo Clinic research??? I had many of the symptoms and would be happy to participate, but I must be fairly stupid as I can’t find out where I would go do this…???

  • What about these serology studies out of Californa. Both of them concluded the far more people have been infected than reported by the government. Like multiples of 40 to 80 times higher. I believe your profession calls this penetrance. Doesn’t this mean that Covid-19 death rates are far lower than published? If the threat from infection isn’t all that dangerous, shouldn’t response policy be aimed at physically increasing hospital capacity rather than protecting each and every American? I don’t see the need to stop working if the virus isn’t all that deadly to me, I do see a need to increase treatment/hospital capacity because Sar-2 spreads so fast and overwhelms hospitals. Is this a fair interpretation of these new serology studies?

  • Order your own COVID -19 Antibody (IgG) blood test in the link below! No doctor or insurance is needed. Pay online and receive your lab requisition by email. It couldn’t be any easier. Use promo code COVID19AB at checkout for a discounted price. Also check the test directory for hundreds of other blood test that you can order!
    https://www.ultalabtests.com/hemovative/Shop/Items/Item/COVID-19-Antibody-IgG-Immunoassay?q=Mg%3D%3D

  • Enforcing a lie!! Look at the numbers people!!! Someone dies of a heart attack Oh he died with covid! Die with stroke Oh Covid killed him! Blaming deaths on lies to fudge numbers to make the lie look real!! Toothache covid, headache covid, gas covid, toe blister covid, back pain covid, tired covid, fever covid, shaky covid, stomach pain covid, lie after lie after lie. Then they say six feet keep six feet then turn around and say its airborne which a virus can’t do. Like a virus can measure Oh he got covid because he was 5 feet and 3/4 inches from the dude in front of him. Or the stupid little sheilds at stores like it wont go around if it was real!!mask dont help, yes it does, well not really, woops better wear a mask. oh yeah fruit is getting covid, pets, etc theyre saying any and everything and people are BELIEVING it even when they change their story over and over and over. But let me tell you the truth about it all! Its not about the “virus” its about control. If you dont get the vaccine you cant buy or sell etc now where have we heard that????? Hmm?
    Everyone must get it rich, poor, people in prison, young, old every man woman and child. Hmmmm…… Sounds very familiar. Even talking about locking people up for not getting it and some say kill those who refuse the vaccine hmmmmm????? Now where did we hear that? Oh yeah in GOD’S WORD THE MARK OF THE BEAST!!!! REFUSE THE VACCINE!!! YOUR ETERNAL LIFE DEPENDS ON IT!!
    JESUS IS AT THE DOOR PLEASE CHOOSE HIM TODAY!!
    Covid19 the best lie going. Oh and check this out covid19 = COV(certificate of vaccination) id( identification) 19(AI/artificial intelligence)
    So lets see the vaccine is to give you a certificate of vaccination that you cant buy or sell without the certificate thats digitally implanted along with your national ID being tracked and traced by AI (artificial intelligence) Wow!!!! Wake up people wake up!!!!! Please seek JESUS and hang tight the beast is here!!!

  • There is a small window of time that this test is accurate. Virtually useless if you wait to long after an illness to know if it was covid or not.

  • There are over 200 commercial COVID-19 antibody tests for binding antibodies, but only one in the market tests for neutralizing antibody. The cPass test is patented and developed by Duke-NUS Medical School of Singapore and can show results within one hour with “100% accuracy.”

  • There are 300,000+ people in the U.S that have been tested positive for Covid 19 and recovered. How many studies (completed or active) for the half life of SARS-2 antibodies are there? What are the current findings/progress? If there are at least observational studies that indicate reinfection is unlikely, wouldn’t that give more value to antibody identifier testing? Also, is there any statistically significant evidence of Covid 19 recovered healthcare workers being reinfected after returning to work? Please point me in the direction of at least a peer reviewed paper on any of the above.
    Lastly, given that the economy is likely going to dictate reopening (people going back to work and shopping), it doesn’t sound like having a working and available antibody identifier test widely available to the public would be a false sense of security, quite the opposite. At least we would have a working test for the progression and path of the virus. It would help straighten out the metrics we currently have that are really not much better than guesstimates anyway. Would it also be valuable data to have if long term complications are identified after supposed recovery, especially if asymptomatic “recovered” people are at risk of later complications?

  • If you have specific IgG COVID-19 antibodies at high enough concentrations, chances are very much scientifically speaking that you do have a developed immunity. It is irresponsible and illogical to think otherwise.

  • Great video, i was just wondering if you could answer a question i have been debating with my family. Hypothetically, if 1% of the worlds population have had corona virus. You take a 99% accurate antibody test and are positive. How safe is it to mix with infected people, assuming antibodies indicate immunity? What if the test was only 95% accurate?

  • How come medical science STILL doesn’t understand how ANTI-BODIRS work? Is this a joke? They haven’t figured out this BASIC level of BIOLOGY yet. This is pathetic.