C-section, Antibiotics, Formula Feeding Alter Baby s Useful Microbes

 

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Pregnancy & Postpartum C-section, Antibiotics, Formula Feeding Alter Baby’s Helpful Microbes When babies are born, the birth process covers their bodies with countless microbes that play crucial roles in their future health. But a new study suggests that these “microbiomes” are altered by cesarean births, antibiotics and formula feeding. WEDNESDAY, June 15, 2016 (HealthDay News) When babies are born, the birth process covers their bodies with countless microbes that play crucial roles in their future health.

But a new study suggests that these “microbiomes” are altered by cesarean births, antibiotics and formula feeding. A new analytical approach, described in open-access journal Frontiers in Pediatrics, shows how different interventions cesarean section, formula feeding, and antibiotics can alter an infant’s. C-Section Babies Are Missing Key Microbes.

A U.K. study provides the best evidence yet that the way infants are born can alter their microbiome—but the health effects are unclear. C-section, formula feeding affect babies’ gut bacteria. 130211-anitakozyrskyj-banner. UAlberta epidemiologist Anita Kozyrskyj and her team found that healthy babies born by C-section or fed by formula had a different makeup of gut bacteria from that of babies born vaginally or breastfed. (Edmonton) Caesarean section delivery and formula feeding appear to change the bacteria footprint in babies’ guts.

Disruption to the infant microbiome from modern practices like antibiotics use, bottle feeding and elective C-section births has been associated with conditions such as asthma, allergies, type 1. Birth by C-section, exposure to antibiotics and formula feeding slow the development and decrease the diversity of a baby’s microbes through the first year of life. That is the finding of a study. Exposing babies delivered by C-section to fluids from the mother’s birth canal enriched the babies’ microbes to levels more typical of babies born vaginally. Larger studies with further follow-up will be needed to determine the long-term health consequences of the microbial transfer procedure.

Mothers who have C-sections also tend to start breast-feeding later and require antibiotics, both of which could also affect the baby’s microbiome. In the new study, researchers analyzed DNA from. Pregnant women get antibiotics to fight Group B strep bacteria and to prevent infection after a C-section, and newborns get dosed to prevent a rare eye.

List of related literature:

Infants treated with a broadspectrum antibiotic during the first 4 days of life show reduced colonization of the gut with Bifidobacterium and unusual colonization of Enterococcus in the first week compared with infants who have not been treated with antibiotics.

“Breastfeeding Management for the Clinician” by Marsha Walker
from Breastfeeding Management for the Clinician
by Marsha Walker
Jones & Bartlett Learning, 2016

Gut colonization is abnormal following caesarean section, formula milk feeding and antibiotic treatment.

“The Science of Paediatrics: MRCPCH Part 1 Mastercourse” by Tom Lissauer, Will Carroll
from The Science of Paediatrics: MRCPCH Part 1 Mastercourse
by Tom Lissauer, Will Carroll
Elsevier, 2016

Breastfed infants have a lower gut pH (acidic environment) of approximately 5.1–5.4 throughout the first 6 weeks,which is dominated by Bifidobacterium with reduced pathogenic (disease-causing) microbes such as Escherichia coli,bacteroides, clostridia, and streptococci.

“Breastfeeding Management for the Clinician: Using the Evidence” by Marsha Walker
from Breastfeeding Management for the Clinician: Using the Evidence
by Marsha Walker
Jones & Bartlett Learning, 2010

C-sections, antibiotics, and formula feeding may alter the development of the microbiome and have been linked to increased metabolic and immune issues [7].

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from Integrative and Functional Medical Nutrition Therapy: Principles and Practices
by Diana Noland, Jeanne A. Drisko, Leigh Wagner
Springer International Publishing, 2020

In this Swedish hospital setting, where early maternal contact was encouraged, infants demonstrated rooting, areolar grasp, and latching on as early as 28 weeks; nutritive sucking (as defined by intake of 5 mL or greater volume) from 30.6 weeks; and repeated swallowing at 31 weeks.

“Breastfeeding and Human Lactation” by Karen Wambach, Jan Riordan
from Breastfeeding and Human Lactation
by Karen Wambach, Jan Riordan
Jones & Bartlett Learning, 2016

Anaerobic organisms may also cause infection for a woman who requires a cesarean birth, and medications such as clindamycin or metronidazole may be prescribed (American Academy of Pediatrics [AAP] & ACOG, 2012; Simhan, Iams, & Romero, 2012).

“Foundations of Maternal-Newborn and Women's Health Nursing” by Sharon Smith Murray, MSN, RN, C, Emily Slone McKinney, MSN, RN, C
from Foundations of Maternal-Newborn and Women’s Health Nursing
by Sharon Smith Murray, MSN, RN, C, Emily Slone McKinney, MSN, RN, C
Elsevier Health Sciences, 2013

The microbiota in breastfed infants is usually dominated by bifidobacteria within a few days, but following a short delay they also reach high numbers in formula-fed infants (Harmsen et al., 2000a; Favier et al., 2002).

“Functional Dairy Products” by Maria Saarela
from Functional Dairy Products
by Maria Saarela
Elsevier Science, 2007

The management of infants depends on a number of factors: the infant’s clinical status; the presence or absence of maternal chorioamnionitis; the duration of penicillin, ampicillin, or cefazolin IAP before delivery, if indicated; the duration of membrane rupture, and the infant’s gestational age.

“Principles and Practice of Pediatric Infectious Diseases E-Book” by Sarah S. Long, Charles G. Prober, Marc Fischer
from Principles and Practice of Pediatric Infectious Diseases E-Book
by Sarah S. Long, Charles G. Prober, Marc Fischer
Elsevier Health Sciences, 2017

Within 8 to 12 hours after delivery, the newborn typically has been colonized by bacteria such as streptococci, staphylococci, and lactobacilli, acquired primarily from its mother.

“Foundations in Microbiology' 2007 Ed.(sixth Edition)2007 Edition” by Talaro, Kathleen Park
from Foundations in Microbiology’ 2007 Ed.(sixth Edition)2007 Edition
by Talaro, Kathleen Park
Rex Bookstore, Inc.,

Minimize the use of antibiotics with breast-feeding because of the risk of altering the baby’s intestinal flora.

“Dentist's Guide to Medical Conditions and Complications” by Kanchan Ganda
from Dentist’s Guide to Medical Conditions and Complications
by Kanchan Ganda
Wiley, 2011

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
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7 comments

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  • What an AMAZING video on different aspects of Gut Microbiome! The animation and the valuable information together gives a strong impact on Child Health. This initiative of great professionals coming together to serve our community is unique and worth performing. The research is very effective and seems to have an enormous task on the future generation. Let’s make this world a better place to live by treating children in the right way with advanced technology. I wish to involve in the research and contribute to our society. Thanks for the powerful video.

  • Traducción completa al español: Nuestro cuerpo es huésped de trillones de bacterias y otros pequeños organismos que solo pueden ser vistos con un microscopio, el vasto universo de microorganismos que viven dentro y sobre nuestro cuerpo, es conocido como la microbioma humana.

    Ahora sabemos que este microbioma y particularmente los microorganismos intestinales juegan un papel clave en cada aspecto de la salud y bienestar, especialmente durante la niñez. Desde el nacimiento, los microorganismos en el intestino llevan a cabo funciones importantes como protegernos de microorganismos patógenos, digerir y absorber los nutrientes de los alimentos y ayudar al desarrollo del sistema inmune del niño para defenderse de infecciones y enfermedades.

    El estudio CHILD (cohorte) es un estudio canadiense de investigación, el cual ha estado estudiando y siguiendo el desarrollo de 3,500 niños en Canadá, desde el embarazo hasta edad para asistir a la escuela y mas allá. Al dar seguimiento a estos niños y sus familias durante muchos años, CHILD ha hecho descubrimientos emocionantes sobre cómo el tipo y el balance de ciertos microorganismos condiciona la salud. Cambios en el microbioma podrían parcialmente explicar las tasas de cambio sobre asma, alergias, obesidad y otras enfermedades crónicas.

    Entre otros estudios, la investigación de CHILD ha encontrado que la forma en que los bebés nacen puede afectar el microbioma intestinal, los bebés nacidos por cesárea tienen un microbioma intestinal distinto en comparación con los niños que nacieron vía vaginal, expuestos a microorganismos de la madre por el canal de parto.

    Los bebés de mamás que recibieron antibióticos durante el parto, también se encuentran propensos a tener cambios en su microbioma intestinal, mientras los antibióticos ayudan a eliminar bacterias que causan infecciones, también puede extinguir bacterias beneficiosas, lo cual propicia que los niños tengan mayor riesgo de desarrollar alergias a alimentos y otras condiciones posteriormente.

    CHILD es uno de los primeros estudios en identificar microorganismos específicos que puedan estar relacionados con el desarrollo de asma, al analizar bacterias intestinales en bebés, se ha encontrado que los infantes con mayor riesgo de desarrollar asma, tienen menores niveles de 4 bacterias específicas en sus primeros 3 meses de edad: faecalibacterium, lachnospira, veillonela y rothia, apodados FLVR para abreviar. No está claro aún porqué algunos infantes tienen niveles bajos de bacterias FLVR en su vida temprana, pero al descubrirlo los investigadores podrían predecir qué niños están en riesgo de desarrollar asma y tal vez incluso prevenir su desarrollo.

    Otro hallazgo del estudio CHILD revela que lo que los bebés ingieren también afecta su microbioma intestinal, la leche materna es un alimento muy especializado para los bebés y su microbioma intestinal. Bebés alimentados con leche materna tienen mayor proporción de bacterias benéficas y menor proporción de bacterias relacionadas con obesidad y otros desórdenes, lo que sugiere que el amamantar a los bebés puede influenciar su microbioma intestinal y ayudar a protegerlo de desarrollar obesidad en la niñez temprana.

    Factores en todo el ambiente como son el uso de productos de limpieza o la presencia de una mascota peluda en casa, podrían también afectar el microbioma intestinal del bebé. Los investigadores del estudio CHILD han encontrado que niños viviendo en casas dónde se desinfecta con limpiadores de superficies al menos una vez por semana son 2 veces más propensos a alteraciones en su microbioma, lo cual fue asociado con sobrepeso a los 3 años de edad. Por otro lado, tener una mascota puede influenciar el microbioma intestinal de forma positiva. El estudio CHILD encontró que bebés de familias que viven con mascotas peludas, especialmente perros, tienden a tener más altos niveles de dos tipos de bacterias específicas y esto estuvo asociado con menor riesgo de desarrollar alergias y obesidad.

    Todos estos hallazgos del estudio CHILD están ayudando a los padres, a los profesionales de la salud y a la comunidad a entender qué constituye un intestino sano en los bebés. Y en el futuro, nos ayudará a todos a hacer decisiones informadas sobre cómo construir un fuerte y sano microbioma en la niñez temprana con el objetivo de reducir los problemas de salud posteriores.

  • Well for some. one with a little brains and IQ… The name is enough to decide… “Formula Milk”…. The best thing for baby is mothers brest milk or milk not these dirty chemicals…

  • I hope this information becomes more wide spread. They should be swabbing all C-Section babies just in case. Since there is already evidence it helps and works.

  • Have you thought about doing a fecal transplant? I thought about it. I have health issues. Was C section baby almost died at birth. Also was mostly bottle fed.

  • Great video guys! Just one small thing. Try using simpler music, which you did for the most part except near the beginning. It becomes a distraction. Keep up the fine work!

  • If you had a c-section, or are having a planned c-section, which of the points highlighted in this video have made you sit up and take note of information you were previously unaware of?