Hormones and Osteoporosis
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Hormones and Healthy Bones
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Introduction to Bioidentical Hormones for Bone Health
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Treating Osteoporosis or Low Bone Density
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Estrogen | Reproductive system physiology | NCLEX-RN | Khan Academy
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Osteoporosis in Postmenopausal Women Mode of Action Animation
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When you have sufficient levels of estrogen, that estrogen helps kill off the breakdown cells (the osteoclasts) so you have less cells breaking down bone in your body. That estrogen also helps protect the cells that build your bone (osteoblasts) so they don’t die off. The major physiological effect of estrogen is to inhibit bone resorption. Bone cells have two kinds of intracellular steroid receptors for estrogen.
When estrogen binds to the receptors, various genes become active. Estrogen also has effects that do not depend on activating the DNA. Estrogen and bone health in men and women. Estrogen is the key regulator of bone metabolism in both men and women. Menopause and the accompanying loss of ovarian estrogens are associated with declines in bone mineral density (BMD): 10-year cumulative loss was 9.1% at the femoral neck and 10.6%, lumbar spine.
Estradiol concentrations also pre. Estrogen plays an important role in the growth and maturation of bone as well as in the regulation of bone turnover in adult bone. During bone growth estrogen is needed for proper closure of epiphyseal growth plates both in females and in males. Also in young skeleton estrogen deficiency leads to increased osteoclast formation and enhanced bone resorption. Estrogen is a sex hormone that is essential to female bone health because it promotes the activity of osteoblasts, which are cells that produce bone.
When estrogen levels drop during menopause, the osteoblasts aren’t able to effectively produce bone. Estrogen replacement therapy used to be the only FDA-approved treatment to prevent osteoporosis. Hormones and Bones Hormones are really important to bone strength.
Hormones are chemicals made by glands that travel throughout the body and have many effects on growth, maturation, energy, weight, and bone strength. Sex hormones (estrogen made in the ovary of females and testosterone made by the testes in males) control ability to reproduce. The 2008 guideline based its recommendation on studies showing estrogen decreased fracture risk—but, as the 2017 guideline points out, “many of these studies focused on postmenopausal women with low bone density, or on postmenopausal women in general rather than those with established osteoporosis.”. Systemic estrogen helps protect against the bone-thinning disease called osteoporosis.
However, doctors usually recommend medications called bisphosphonates to treat osteoporosis. But estrogen therapy may help if you either can’t tolerate or aren’t benefiting from other treatments. Experience early menopause or have estrogen deficiency.
Estrogen is the key regulator of bone metabolism in both men and women. Menopause and the accompanying loss of ovarian estrogens are associated with declines in bone mineral density (BMD): 10-year cumulative loss was 9.1% at the femoral neck and 10.6%, lumbar spine. Estradiol concentrations also predict fractures.
Estrogen is the key regulator of bone metabolism in both men and women. and the accompanying loss of ovarian estrogens are associated with declines in bone mineral density (BMD): 10-year cumulative loss was 9.1% at the femoral neck Estradiol concentrations also predict fractures.
List of related literature:
|from The Whole-Body Approach to Osteoporosis: How to Improve Bone Strength and Reduce Your Fracture Risk|
|from Applying Sport Psychology: Four Perspectives|
|from Encyclopedia of Human Nutrition|
|from The Encyclopedia of Nutrition and Good Health|
|from Linda Page’s Healthy Healing: A Guide to Self-healing for Everyone|
|from Netter’s Sports Medicine E-Book|
|from Apley’s Concise System of Orthopaedics and Fractures|
|from Comprehensive Gynecology E-Book|
|from Sports Nutrition for Endurance Athletes, 3rd Ed.|