What You Must Know About ICSI-In vitro fertilization treatments


Intracytoplasmic Sperm Injection (ICSI): The Procedure

Video taken from the channel: City Fertility


ICSI Is it your key to IVF success?

Video taken from the channel: Infertility TV


IVF Animation ICSI

Video taken from the channel: Prof. Dr. Selman Laçin


ICSI IVF Treatment Procedure Step By Step Video What is ICSI?

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What Is The Difference Between IVF and ICSI? | The Zita West Clinic

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Do you have to do ICSI with IVF? What’s the difference?

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IVF ICSI Procedure Important things you need to know

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ICSI-IVF is typically used in cases of severe male infertility, including: 2  Very low sperm count (also known as oligospermia) Abnormally shaped sperm (also known as teratozoospermia) Poor sperm movement (also known as asthenozoospermia). ICSI differs from IVF in one primary way. With IVF, fertility doctors mix many sperm together in a dish with a viable, healthy egg.

Typically, a healthy sperm then permeates the lining of the egg and fertilizes it. But with direct sperm injection, the fertilization process is more straightforward. In fact, a natural pregnancy also carries a certain small degree of risk with it so that apprehension should not hinder you from researching into this treatment option. The most commonly feared birth defect associated with ICSI is that of passing the male infertility down to a male child.

ICSI-IVF is a specialized form of in vitro fertilization, which is most commonly used in many cases where severe male infertility is after that many repeated failed fertilization attempts with conventional or sometimes unconventional IVF, or after the process of egg freezing (oocyte preservation). ICSI can also help couples that attempted IVF but had what’s known as “failed fertilization.” Failed fertilization happens when more than one. ICSI can increase IVF success rates but the procedure is not perfect. Here are some more common risks associated with ICSI.

IVF can also be performed with ICSI. The major birth defects seen in babies born via IVF and/or ICSI included heart defects and malformations of the urogenital tract, such as hypospadias (an. 11 Things You Should Know Before Considering IVF It’s the most effective treatment for infertility, but it’s no walk in the park. By Amy Marturana Winderl, C.P.T. IVF was the technique that was developed first and ICSI is a variation of this technique. From the viewpoint of a patient, not much changes with reference to scans, superovulation injections, blood tests, egg collection as well as the actual embryo transfer.

The only difference is that which takes place in the lab. ICSI is an acronym for intracellular sperm injection. It is performed as part of an IVF procedure.

In IVF without ICSI, eggs and sperm are combined in the embryology laboratory. A sperm cell will manage to pierce the wall of an egg and fertilize it.

List of related literature:

Neonatal and obstetric outcome of pregnancies conceived by ICSI or IVF.

“Handbook of In Vitro Fertilization” by David K. Gardner, Carlos Simón
from Handbook of In Vitro Fertilization
by David K. Gardner, Carlos Simón
CRC Press, 2017

– Intracytoplasmic sperm injection (ICSI) is performed in conjunction with IVF for males with severe abnormalities (i.e., <5 million sperm) or those who have failed to conceive with IUI.

“The 5-Minute Clinical Consult 2020” by Frank J. Domino, Robert A. Baldor, Jeremy Golding, Mark B. Stephens
from The 5-Minute Clinical Consult 2020
by Frank J. Domino, Robert A. Baldor, et. al.
Wolters Kluwer Health, 2019

During IVF another technique called intracytoplasmic sperm injection (ICSI) can isolate the most vital sperm, even only one excellent sperm, and inject it into an egg.

“Before Your Pregnancy: A 90-Day Guide for Couples on How to Prepare for a Healthy Conception” by Amy Ogle, Lisa Mazzullo, Mary D'Alton
from Before Your Pregnancy: A 90-Day Guide for Couples on How to Prepare for a Healthy Conception
by Amy Ogle, Lisa Mazzullo, Mary D’Alton
Random House Publishing Group, 2011

Intracytoplasmic sperm injection (ICSI), which was introduced in 1992, offered couples with severe male infertility and those with fertilization failure after conventional IVF a realistic chance of parenthood.57 With the advent of ICSI, both SUZI and PZD were abandoned.

“Endocrinology E-Book: Adult and Pediatric” by J. Larry Jameson, Leslie J. De Groot
from Endocrinology E-Book: Adult and Pediatric
by J. Larry Jameson, Leslie J. De Groot
Elsevier Health Sciences, 2010

In vitro fertilization (IVF), in which eggs are removed from the woman, fertilized and then placed in the woman’s uterus, bypassing the fallopian tubes, involve several steps that can increase abnormal methylation and demethylation events.

“Reproductive and Developmental Toxicology” by Ramesh C. Gupta
from Reproductive and Developmental Toxicology
by Ramesh C. Gupta
Elsevier Science, 2011

If the iCSi procedure is successful, the fertilized egg is transferred to the woman’s uterus using normal ivF procedures.

“Biomedicalization: Technoscience, Health, and Illness in the U.S.” by Adele E. Clarke, Laura Mamo, Jennifer Ruth Fosket, Jennifer R. Fishman, Janet K. Shim, Elianne Riska
from Biomedicalization: Technoscience, Health, and Illness in the U.S.
by Adele E. Clarke, Laura Mamo, et. al.
Duke University Press, 2010

In addition, efficient IVM and IVF procedures are important for the development of other biotechnologies such as embryo splitting, sexing, nuclear transfer, and gene transfer.

“Current Therapy in Large Animal Theriogenology E-Book” by Robert S. Youngquist, Walter R. Threlfall
from Current Therapy in Large Animal Theriogenology E-Book
by Robert S. Youngquist, Walter R. Threlfall
Elsevier Health Sciences, 2006

A micromanipulation technique of the follicle called intra­cytoplasmic sperm injection (ICSI) makes it possible to achieve fertilization even with few or poor-quality sperm by introducing sperm beneath the zona pellucida directly into the egg.

“Maternity and Women's Health Care E-Book” by Deitra Leonard Lowdermilk, Shannon E. Perry, Mary Catherine Cashion, Kathryn Rhodes Alden
from Maternity and Women’s Health Care E-Book
by Deitra Leonard Lowdermilk, Shannon E. Perry, et. al.
Elsevier Health Sciences, 2014

Among couples whose male partner has very low numbers of motile sperm, high fertilization rates can be achieved using intracytoplasmic sperm injection (ICSI).

“Medical Physiology, 2e Updated Edition E-Book: with STUDENT CONSULT Online Access” by Walter F. Boron, Emile L. Boulpaep
from Medical Physiology, 2e Updated Edition E-Book: with STUDENT CONSULT Online Access
by Walter F. Boron, Emile L. Boulpaep
Elsevier Health Sciences, 2012

A study in the New England Journal of Medicine in spring 2002 reported the risk of birth defects doubles when IVF procedures include ICSI (intracytoplasmic sperm injection, which is used when sperm are not healthy enough to penetrate the egg on their own).

“The Infertility Cure: The Ancient Chinese Wellness Program for Getting Pregnant and Having Healthy Babies” by Randine Lewis
from The Infertility Cure: The Ancient Chinese Wellness Program for Getting Pregnant and Having Healthy Babies
by Randine Lewis
Little, Brown, 2008

Oktay Kutluk

Kutluk Oktay, MD, FACOG is one of the world's foremost experts in fertility preservation as well as ovarian stimulation and in vitro fertilization for infertility treatments. He developed and performed the world's first ovarian transplantation procedures as well as pioneered new ovarian stimulation protocols for embryo and oocyte freezing for breast and endometrial cancer patients.

Mail: [email protected]
Telephone: +1 (877) 492-3666

Biography: https://medicine.yale.edu/profile/kutluk_oktay/
Bibliography: oktay_bibliography

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  • My clinic called me today and said my 5 mature eggs were fertilized but developing very slow and it isn’t good And want to
    Wait til Tommorow to see if devolpment is any better? Have you ever heard of this? I’m so heart broken

  • Hey…could u please tell me how to have a full term delivery…i m hving bicornuate uterus in which one part has been removed due to non communicating rudimentary horn.
    I have done ivf,3 embryos has been transfered on 5th of this month.
    But on yestrdays scanning only one gestational sac is visible has the diameter of 0.58centi meter.Is it normal?

  • All the steps involved in ICSI are the same ones followed in a regular IVF treatment — except for the fertilization method. ICSI uses one only sperm cell for a single egg, while standard IVF (petri dish) needs hundreds of thousands.

    ICSI enables pregnancy to be achieved successfully in couples affected by severe male-factor infertility. The male partner provides a semen sample or undergoes a surgical retrieval procedure (for men who have little/no sperm in the semen or men who are not able to ejaculate). Best sperm cells are selected for fertilization purposes.

    Instead of merely combining the prepared eggs and sperm in a petri dish and waiting for fertilization to take place on its own, ICSI allows doctors to use powerful microscopes and precise equipment to select individual, healthy sperm cells and place them directly into each collected egg.

    ICSI has also proven to be very successful in cases of female infertility, like unexplained infertility, poor egg quality, low egg production, fertilization failure, or fertilization of cryopreserved eggs. Being a critical aspect of IVF success due to the high fertilization rate (90%), some clinics apply ICSI routinely in all IVF procedures.

  • In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are two very similar assisted reproduction techniques, although they differ from each other and are indicated in different cases

  • Sometimes, a good number of eggs are retrieved, and sperm counts look healthy, but no eggs get fertilized. In this case, during the next IVF cycle, ICSI may be tried.

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  • Clomid pills and IUI treatment is the max I would offer. This IVF ICSI thing looks too artificial. I am not surprised if IVF kids start to get cancer when they hit age 45.

  • I have appointment in Mexico for IVF+ICSI, we are very nervous!! Since my DH’s counts are very low our dr is recommending ICSI to assist the IVF process. Any info/tips/experience anyone can provide would be greatly appreciate!

  • Sometimes you can get pregnant through a normal IVF but sometimes you need an ICSI, specially when your male partner is the one who has infertility problems. We thought we may need an ICSI before going to Ingenes in Mexico, but we ended up with just a normal IVF and we finally had our baby.

  • Very good! It made it so easy to understand. People need to look for these videos first. Before going for these procedures. Helps them to have a better outlook. It’s brilliantly explained. Thanks for this.